Targeting Eph/ephrin system in cancer therapy.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.07.029
Abstract: It is well established that the Eph/ephrin system plays a central role in the embryonic development, with minor implications in the physiology of the adult. However, it is overexpressed and deregulated in a variety of… read more here.
Keywords: eph ephrin; system; ephrin system; targeting eph ... See more keywords
Protection by the Eph–Ephrin System Against Mesenteric Ischemia-Reperfusion Injury
Sign Up to like & getrecommendations! Published in 2017 at "SHOCK"
DOI: 10.1097/shk.0000000000000890
Abstract: ABSTRACT Mesenteric ischemia-reperfusion (I/R)-induced injury targets primarily endothelial and epithelial cells, leading to a cascade of inflammatory events, eventually culminating in life-threatening syndromes. Hitherto, the role of Eph, the largest family of tyrosine kinase receptors,… read more here.
Keywords: eph ephrin; mesenteric ischemia; ephrin system; ephrin ... See more keywords
The EPH/Ephrin System in Pancreatic Ductal Adenocarcinoma (PDAC): From Pathogenesis to Treatment
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24033015
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a major concern for health care systems worldwide, since its mortality remains unaltered despite the surge in cutting-edge science. The EPH/ephrin signaling system was first investigated in the 1980s. EPH/ephrins… read more here.
Keywords: system; eph ephrin; ephrin system; pancreatic ductal ... See more keywords