Vandetanib drives growth arrest and promotes sensitivity to imatinib in chronic myeloid leukemia by targeting ephrin type‐B receptor 4
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DOI: 10.1002/1878-0261.13270
Abstract: The oncogenic role of ephrin type‐B receptor 4 (EPHB4) has been reported in many types of tumors, including chronic myeloid leukemia (CML). Here, we found that CML patients have a higher EPHB4 expression level than… read more here.
Keywords: imatinib; growth; ephrin type; vandetanib ... See more keywords
The prognostic value of ephrin type-A2 receptor and Ki-67 in renal cell carcinoma patients
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DOI: 10.1097/md.0000000000020191
Abstract: Abstract Patients with renal cell carcinoma (RCC), the most common malignant renal epithelial tumor, usually present with advanced disease and unpredicted clinical behavior. The receptor tyrosine kinase, ephrin type-A receptor 2 (EphA2) was found to… read more here.
Keywords: expression; rcc; renal cell; cell carcinoma ... See more keywords
Monocyte proinflammatory phenotypic control by ephrin type A receptor 4 mediates neural tissue damage
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DOI: 10.1172/jci.insight.156319
Abstract: Circulating monocytes have emerged as key regulators of the neuroinflammatory milieu in a number of neuropathological disorders. Ephrin type A receptor 4 (Epha4) receptor tyrosine kinase, a prominent axon guidance molecule, has recently been implicated… read more here.
Keywords: monocyte; neural tissue; ephrin type; tissue damage ... See more keywords