Synthesis of 3-epi-Hypatulin B Featuring a Late-Stage Photo-Oxidation in Flow.
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DOI: 10.1021/acs.orglett.2c00689
Abstract: A synthesis of 3-epi-hypatulin B, a highly oxygenated and densely functionalized bicyclic scaffold, is reported. The carbon skeleton was prepared by functionalization of a cyclopentanone and an intramolecular Mukaiyama aldol reaction. Highlights include a late-stage… read more here.
Keywords: epi hypatulin; synthesis; flow; late stage ... See more keywords