Recording of isolated very delayed potentials on the right ventricular epicardium in a patient with Brugada syndrome
Sign Up to like & getrecommendations! Published in 2017 at "HeartRhythm Case Reports"
DOI: 10.1016/j.hrcr.2017.05.001
Abstract: Introduction Epicardial mapping revealed the existence of abnormal potentials on the right ventricular outflow tract (RVOT) in patients with Brugada syndrome. It is reported that tissues of the RVOT epicardium from open-chest biopsy and autopsy… read more here.
Keywords: epicardium; right ventricular; isolated delayed; potentials right ... See more keywords
Local activation delay exacerbates local J-ST elevation in the epicardium: Electrophysiological substrate in Brugada syndrome
Sign Up to like & getrecommendations! Published in 2017 at "HeartRhythm Case Reports"
DOI: 10.1016/j.hrcr.2017.10.005
Abstract: Introduction The mechanisms of J-ST elevation in the right precordial leads in patients with Brugada syndrome (BrS) remain controversial (ie, repolarization vs depolarization hypotheses). Recently, epicardial substrate ablation for late fractionated potentials and a low-voltage… read more here.
Keywords: epicardium; surface ecgs; brugada syndrome; unipolar electrodes ... See more keywords
Coordination of endothelial cell positioning and fate specification by the epicardium
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-24414-z
Abstract: The organization of an integrated coronary vasculature requires the specification of immature endothelial cells (ECs) into arterial and venous fates based on their localization within the heart. It remains unclear how spatial information controls EC… read more here.
Keywords: coordination endothelial; fate specification; epicardium; endothelial cell ... See more keywords
A small molecule screen identifies novel inducers of EMT that may increase epicardium-driven repair of the heart
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.3651
Abstract: Since the adult heart has minimal capacity to repair itself, myocardial infarction often leads to pathological remodelling and consequently the development of heart failure. Unfortunately, no therapy is available to restore damaged heart tissue. The… read more here.
Keywords: epicardium; heart; emt; small molecule ... See more keywords
Epicardium in Heart Development.
Sign Up to like & getrecommendations! Published in 2019 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a037192
Abstract: The epicardium, the outermost tissue layer that envelops all vertebrate hearts, plays a crucial role in cardiac development and regeneration and has been implicated in potential strategies for cardiac repair. The heterogenous cell population that… read more here.
Keywords: epicardium; heart development; biology; development ... See more keywords
‘Vanishing’ fragmented potential at the epicardium in a patient with Brugada syndrome
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-249054
Abstract: A man in his 40s with Brugada syndrome underwent catheter ablation for ventricular fibrillation. When we performed epicardial mapping again to check for residual ablation sites after ablation, a remarkable reproducible fragmented potential was observed… read more here.
Keywords: fragmented potential; vanishing fragmented; ablation; air ... See more keywords
Porcine Organotypic Epicardial Slice Protocol: A Tool for the Study of Epicardium in Cardiovascular Research
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.920013
Abstract: The epicardium has recently gained interest in the cardiovascular field due to its capacity to support heart regeneration after ischemic injury. Models to study the epicardium of large animals in vitro are limited and mainly… read more here.
Keywords: research; physiology; porcine; epicardium ... See more keywords