Oat β-glucan ameliorates epidermal barrier disruption by upregulating the expression of CaSR through dectin-1-mediated ERK and p38 signaling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.07.002
Abstract: The integrity of the epidermal barrier and the maintenance of barrier homeostasis depend on the dynamic balance between the proliferation and differentiation of keratinocytes. Calcium (Ca2+) plays a crucial role in maintaining a balance of… read more here.
Keywords: barrier; oat glucan; erk p38; epidermal barrier ... See more keywords
Cystatin immunoreactivity in cornifying layers of the epidermis suggests a role in the formation of the epidermal barrier in amniotes.
Sign Up to like & getrecommendations! Published in 2018 at "Zoology"
DOI: 10.1016/j.zool.2018.02.003
Abstract: The presence and localization of cystatin, a cysteine protease inhibitor involved in barrier formation in human and mice epidermis, has been studied in the epidermis of piscine and terrestrial vertebrates using a mouse monoclonal antibody.… read more here.
Keywords: pre corneous; corneous layer; formation; cystatin ... See more keywords
Cutibacterium acnes regulates the epidermal barrier properties of HPV-KER human immortalized keratinocyte cultures
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-69677-6
Abstract: Our skin provides a physical barrier to separate the internal part of our body from the environment. Maintenance of complex barrier functions is achieved through anatomical structures in the skin, the stratified squamous epithelium specialized… read more here.
Keywords: barrier; acnes regulates; cutibacterium acnes; epidermal barrier ... See more keywords
Impact of Gloves and Mask Use on Epidermal Barrier Function in Health Care Workers
Sign Up to like & getrecommendations! Published in 2021 at "Dermatitis"
DOI: 10.1097/der.0000000000000682
Abstract: Background Coronavirus disease 2019 has rapidly spread all over the world. Personal protective equipment (PPE) including masks and gloves is needed to avoid transmission. Adverse skin reactions associated with PPE have been described, but there… read more here.
Keywords: barrier function; epidermal barrier; gloves mask; barrier ... See more keywords
Atopic dermatitis is associated with reduced corneodesmosin expression: role of cytokine modulation and effects on viral penetration
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Dermatology"
DOI: 10.1111/bjd.15010
Abstract: The skin epidermal barrier plays a critical role in preventing allergen and microbial penetration into the human body.1 Atopic dermatitis (AD) is characterized by epidermal barrier defects and recurrent microbial skin infections.1 Recent studies indicate… read more here.
Keywords: atopic dermatitis; epidermal barrier; role; penetration ... See more keywords
The impact of stress on epidermal barrier function: an evidence‐based review
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Dermatology"
DOI: 10.1111/bjd.17605
Abstract: The epidermal barrier functions to limit skin infection and inflammation by inhibiting irritant and immunogen invasion. Abundant evidence suggests that psychological stress stemming from crowding, isolation, nicotine smoking, insomnia, mental arithmetic tasks, physical pain, real‐life… read more here.
Keywords: impact stress; stress epidermal; barrier; evidence ... See more keywords
Effects of skin washing frequency on the epidermal barrier function and inflammatory processes of the epidermis: An experimental study
Sign Up to like & getrecommendations! Published in 2022 at "Contact Dermatitis"
DOI: 10.1111/cod.14119
Abstract: Increased hand hygiene measures during the COVID‐19 pandemic have led to an increased quantum of hand eczema (HE). read more here.
Keywords: epidermal barrier; barrier function; effects skin; washing frequency ... See more keywords
Protein kinases involved in epidermal barrier formation: The AKT family and other animals
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13696
Abstract: Formation of a stratified epidermis is required for the performance of the essential functions of the skin; to act as an outside‐in barrier against the access of microorganisms and other external factors, to prevent loss… read more here.
Keywords: kinases involved; protein kinases; formation; epidermal barrier ... See more keywords
1‐(2‐Hydroxyethyl)‐2‐imidazolidinone, a heparanase and matrix metalloproteinase inhibitor, improves epidermal basement membrane structure and epidermal barrier function
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Dermatology"
DOI: 10.1111/exd.13876
Abstract: Daily exposure to sunlight is known to affect the structure and function of the epidermal basement membrane (BM), as well as epidermal differentiation and epidermal barrier function. The aim of this study is to clarify… read more here.
Keywords: heparanase; epidermal basement; epidermal barrier; barrier function ... See more keywords
Keratinocyte-derived IL-1β induces PPARG down-regulation and PPARD up-regulation in.
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DOI: 10.1111/exd.14323
Abstract: Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors. In skin, PPARs modulate inflammation, lipid synthesis, keratinocyte differentiation and proliferation and thus are important for skin barrier homeostasis. Accordingly, PPAR expression is altered… read more here.
Keywords: barrier; epidermal barrier; expression; barrier impairment ... See more keywords
The Impact of Ultraviolet Radiation on Barrier Function in Human Skin: Molecular Mechanisms and Topical Therapeutics.
Sign Up to like & getrecommendations! Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666171106164916
Abstract: A competent epidermal barrier is crucial for terrestrial mammals. This barrier must keep in water and prevent entry of noxious stimuli. Most importantly, the epidermis must also be a barrier to ultraviolet radiation (UVR) from… read more here.
Keywords: barrier; ultraviolet radiation; barrier function; epidermal barrier ... See more keywords