Master regulatory role of p63 in epidermal development and disease
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DOI: 10.1007/s00018-017-2701-z
Abstract: The transcription factor p63 is a master regulator of epidermal development. Mutations in p63 give rise to human developmental diseases that often manifest epidermal defects. In this review, we summarize major p63 isoforms identified so… read more here.
Keywords: regulatory role; p63 epidermal; epidermal development; p63 ... See more keywords
RIPK4 regulates cell-cell adhesion in epidermal development and homeostasis.
Sign Up to like & getrecommendations! Published in 2022 at "Human molecular genetics"
DOI: 10.1093/hmg/ddac046
Abstract: Epidermal development and maintenance are finely regulated events requiring a strict balance between proliferation and differentiation. Alterations in these processes give rise to human disorders such as cancer or syndromes with skin and annexes defects,… read more here.
Keywords: cell adhesion; ripk4; adhesion; epidermal development ... See more keywords
Epigenetic Mechanisms of Epidermal Differentiation
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DOI: 10.3390/ijms23094874
Abstract: Keratinocyte differentiation is an essential process for epidermal stratification and stratum corneum formation. Keratinocytes proliferate in the basal layer of the epidermis and start their differentiation by changing their functional or phenotypical type; this process… read more here.
Keywords: epidermal differentiation; keratinocyte differentiation; epidermal development; mechanisms epidermal ... See more keywords