Articles with "epidermal necrolysis" as a keyword



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Photodistributed Toxic Epidermal Necrolysis: Case Report and Review of Current Literature.

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Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.1090

Abstract: Importance Cases of photodistributed Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) have been infrequently reported since the first documented case in 1989. This emerging clinical entity and its underlying mechanism have yet to be… read more here.

Keywords: toxic epidermal; report; case report; case ... See more keywords
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Outcomes Associated With Neutropenia and Lymphopenia in Epidermal Necrolysis: A Single-Center Retrospective Study of 147 Patients.

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Published in 2023 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.6262

Abstract: This retrospective cohort study examines the association of lymphocyte and neutrophil levels with treatment outcomes in 147 patients with epidermal necrolysis in France. read more here.

Keywords: outcomes associated; 147 patients; neutropenia lymphopenia; associated neutropenia ... See more keywords
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Biases associated with epidermal necrolysis reporting in pharmacovigilance: An exploratory analysis using World Health Organization VigiBase

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Published in 2021 at "Pharmacoepidemiology and Drug Safety"

DOI: 10.1002/pds.5399

Abstract: Possible biases in pharmacovigilance reporting may impact epidermal necrolysis (EN) and drugs associations. read more here.

Keywords: pharmacovigilance; epidermal necrolysis; biases associated; associated epidermal ... See more keywords
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Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures

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Published in 2017 at "Advances in Therapy"

DOI: 10.1007/s12325-017-0530-y

Abstract: IntroductionStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic conditions occurring in the inpatient setting. There is a lack of consensus regarding appropriate management of SJS and TEN.PurposeThe scientific… read more here.

Keywords: sjs ten; johnson syndrome; epidermal necrolysis; care ... See more keywords
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FR-Ciclosporin as a First-Line Treatment in Epidermal Necrolysis.

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Published in 2019 at "Actas dermo-sifiliograficas"

DOI: 10.1016/j.ad.2018.01.014

Abstract: Please cite this article as: Morgado-Carrasco D, Fustà-Novell X, Iranzo P. FR-Ciclosporin as a First-Line Treatment in Epidermal Necrolysis. Actas Dermosifiliogr. 2019;110:601--603. ∗ Corresponding author. E-mail address: [email protected] (P. Iranzo). associated with high mortality, which… read more here.

Keywords: first line; necrolysis; ciclosporin first; line treatment ... See more keywords
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Stevens-Johnson syndrome and toxic epidermal necrolysis in pregnant patients: A systematic review

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Published in 2020 at "International Journal of Women's Dermatology"

DOI: 10.1016/j.ijwd.2020.04.002

Abstract: Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic emergencies. Although pregnant women comprise a subset of individuals at risk for SJS and TEN development, little is known… read more here.

Keywords: epidermal necrolysis; pregnant patients; toxic epidermal; stevens johnson ... See more keywords
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Vulvovaginal Manifestations in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Prevention and Treatment.

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Published in 2019 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2019.08.031

Abstract: The prevalence of acute vulvovaginal involvement in toxic epidermal necrolysis may be as high as 70%; up to 28% of females will also develop chronic vulvovaginal sequelae. There is little consensus regarding prevention and treatment… read more here.

Keywords: toxic epidermal; prevention treatment; epidermal necrolysis;
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Acute pancreatic injuries: A complication of Stevens-Johnson syndrome/toxic epidermal necrolysis associated with cytotoxic immunocell activation

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Published in 2020 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2020.06.043

Abstract: Abstract Background Complications involving internal organs are usually present in Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However, pancreatic complications are rarely reported and studied. Objective To summarize clinical characteristics of SJS/TEN-associated acute pancreatic… read more here.

Keywords: sjs ten; pancreatic injuries; johnson syndrome; epidermal necrolysis ... See more keywords
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Inhibition of tumor necrosis factor improves conventional steroid therapy for Stevens-Johnson syndrome/toxic epidermal necrolysis.

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Published in 2022 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2022.01.039

Abstract: BACKGROUND Systemic steroid therapies for Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) have been challenged due to their limited benefits. Whether additional tumor necrosis factor (TNF)-α inhibition provides an optimized approach remains unexplored. OBJECTIVE To investigate… read more here.

Keywords: epidermal necrolysis; johnson syndrome; inhibition; therapy ... See more keywords
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Successful dabrafenib transition after vemurafenib-induced toxic epidermal necrolysis in a patient with metastatic melanoma

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Published in 2018 at "JAAD Case Reports"

DOI: 10.1016/j.jdcr.2018.08.003

Abstract: Vemurafenib improves survival in advanced metastatic melanoma, but has rarely been associated with severe skin reactions including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).1, 2 Dabrafenib is a BRAF inhibitor that shares a sulfonamide… read more here.

Keywords: vemurafenib induced; metastatic melanoma; epidermal necrolysis; toxic epidermal ... See more keywords
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Stevens-Johnson syndrome and toxic epidermal necrolysis: risk factors, causality assessment and potential prevention strategies

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Published in 2020 at "Expert Review of Clinical Immunology"

DOI: 10.1080/1744666x.2020.1740591

Abstract: ABSTRACT Introduction: The clinical manifestations of cutaneous adverse drug reactions are variable with different severity. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe cutaneous adverse reactions (SCARs) majorly caused by drugs and… read more here.

Keywords: epidermal necrolysis; johnson syndrome; risk factors; stevens johnson ... See more keywords