Epidermal Stem Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-31206-0_12
Abstract: A multilayered epithelium to fulfil its function must be replaced throughout the lifespan. This is possible due to the presence of multipotent, self-renewing epidermal stem cells that give rise to differentiated cell lineages: keratinocytes, hairs,… read more here.
Keywords: cell; biology; epidermal stem; stem ... See more keywords
Preliminary studies of hair follicle regeneration by injections of epidermal stem cells and dermal papilla cells into nude mice
Sign Up to like & getrecommendations! Published in 2020 at "Cell and Tissue Banking"
DOI: 10.1007/s10561-020-09825-4
Abstract: The ultimate goal of organ regenerative therapy is to reproduce fully functional organs to replace which have been damaged as a result of diseases or injury. Although several studies claimed that using different types of… read more here.
Keywords: hair follicle; papilla cells; cells dermal; epidermal stem ... See more keywords
Laminin 332-Dependent YAP Dysregulation Depletes Epidermal Stem Cells in Junctional Epidermolysis Bullosa.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.04.055
Abstract: Laminin 332-deficient junctional epidermolysis bullosa (JEB) is a severe genetic skin disease. JEB is marked by epidermal stem cell depletion, the origin of which is unknown. We show that dysregulation of the YAP and TAZ… read more here.
Keywords: stem cells; jeb; yap; epidermal stem ... See more keywords
Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization.
Sign Up to like & getrecommendations! Published in 2021 at "Cell stem cell"
DOI: 10.1016/j.stem.2021.05.007
Abstract: Stem cells support lifelong maintenance of adult organs, but their specific roles during injury are poorly understood. Here we demonstrate that Lgr6 marks a regionally restricted population of epidermal stem cells that interact with nerves… read more here.
Keywords: stem cells; wound epithelialization; epidermal stem; stem ... See more keywords
Interplay between epidermal stem cell dynamics and dermal deformation
Sign Up to like & getrecommendations! Published in 2018 at "npj Computational Materials"
DOI: 10.1038/s41524-018-0101-z
Abstract: Tissue growth is a driving force of morphological changes in living systems. Whereas the buckling instability is known to play a crutial role for initiating spatial pattern formations in such growing systems, little is known… read more here.
Keywords: stem; basement membrane; epidermal stem; stem cell ... See more keywords
Spatio-temporal regulation of gene expression defines subpopulations of epidermal stem cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical Society transactions"
DOI: 10.1042/bst20200740
Abstract: The search for epidermal stem cells has gained the momentum as they possess unique biological characteristics and a potential in regeneration therapies. Several transcription factors and miRNAs have been identified as epidermal stem cell markers.… read more here.
Keywords: epidermal stem; temporal regulation; spatio temporal; stem cells ... See more keywords
How and Why the Circadian Clock Regulates Proliferation of Adult Epithelial Stem Cells
Sign Up to like & getrecommendations! Published in 2023 at "Stem Cells"
DOI: 10.1093/stmcls/sxad013
Abstract: Abstract First described in the early 20th century, diurnal oscillations in stem cell proliferation exist in multiple internal epithelia, including in the gastrointestinal tract, and in the epidermis. In the mouse epidermis, 3- to 4-fold… read more here.
Keywords: circadian clock; proliferation; epidermal stem; stem ... See more keywords
The increase of interfollicular epidermal stem cells and regulation of aryl hydrocarbon receptor and its repressors in the skin through hydroporation with anti‐aging cocktail
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.12798
Abstract: Hydroporation is a procedure that involves a subsonic flow of air and microdroplets into the skin. We previously reported that hydroporation treatment with a cocktail solution containing copper‐glycyl‐L‐histidyl‐L‐lysyl, oligo hyaluronic acid, rhodiola extract, tranexamic acid,… read more here.
Keywords: hydroporation; interfollicular epidermal; increase interfollicular; cells regulation ... See more keywords
Hormesis and Epidermal Stem Cells
Sign Up to like & getrecommendations! Published in 2022 at "Dose-Response"
DOI: 10.1177/15593258221119911
Abstract: This paper provides an assessment of hormetic dose responses in epidermal stem cells (EpSCs) in animal models and humans, with emphasis on cell proliferation and differentiation and application to wound healing and aging processes. Hormetic… read more here.
Keywords: hormetic dose; epidermal stem; hormesis; dose responses ... See more keywords
EGFL7 affects the migration of epidermal stem cells in refractory diabetic wounds by regulating Notch signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Regenerative medicine"
DOI: 10.2217/rme-2022-0123
Abstract: Aim: This study aimed to explore the role of EGFL7 in the healing process of refractory diabetic wounds. Methods: Epidermal stem cells (ESCs) were isolated from healthy mice and diabetic mice, identified by immunofluorescence, transfected… read more here.
Keywords: refractory diabetic; egfl7 affects; epidermal stem; diabetic wounds ... See more keywords
BC-Box Motif in SOCS6 Induces Differentiation of Epidermal Stem Cells into GABAnergic Neurons
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21144947
Abstract: The BC-box motif in suppressor of cytokine signaling 6 (SOCS6) promotes the neuronal differentiation of somatic stem cells, including epidermal stem cells. SOCS6 protein belongs to the group of SOCS proteins and inhibits cytokine signaling.… read more here.
Keywords: box motif; differentiation; epidermal stem; stem cells ... See more keywords