Epigallocatechin‐3‐gallate sensitises multidrug‐resistant oral carcinoma xenografts to vincristine sulfate
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DOI: 10.1002/2211-5463.12905
Abstract: Oral squamous cell carcinoma (OSCC) is a very aggressive malignancy, and 50% of patients who receive curative treatment die from the disease or related complications within 5 years. Epigallocatechin‐3‐gallate (EGCG) is the most abundant bioactive… read more here.
Keywords: carcinoma; sensitises multidrug; epigallocatechin gallate; vincristine sulfate ... See more keywords
(−)‐Epigallocatechin‐3‐gallate inhibits human angiotensin‐converting enzyme activity through an autoxidation‐dependent mechanism
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.21932
Abstract: We investigated the molecular mechanisms involved in the angiotensin‐converting enzyme (ACE) inhibition by (−)‐epigallocatechin‐3‐gallate (EGCg), a major tea catechin. EGCg inhibited both the ACE activity in the lysate of human colorectal cancer cells and human… read more here.
Keywords: converting enzyme; angiotensin converting; epigallocatechin gallate; ace ... See more keywords
Low dose epigallocatechin-3-gallate revives doxorubicin responsiveness by a redox-sensitive pathway in A549 lung adenocarcinoma cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.22999
Abstract: Pulmonary cancer confronts the greatest hurdle of resistance against most chemotherapeutic drugs. This may be circumvented with a combination of conventional chemotherapy with bioactive herbal adjuvant. Epigallocatechin-3-gallate (EGCG), was investigated for its chemo-sensitizing property along… read more here.
Keywords: low dose; a549; epigallocatechin gallate; lung adenocarcinoma ... See more keywords
Theaflavin and epigallocatechin‐3‐gallate synergistically induce apoptosis through inhibition of PI3K/Akt signaling upon depolymerizing microtubules in HeLa cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27886
Abstract: Theaflavin (TF) and epigallocatechin‐3‐gallate (EGCG) both have been reported previously as microtubule depolymerizing agents that also have anticancer effects on various cancer cell lines and in animal models. Here, we have applied TF and EGCG… read more here.
Keywords: combination; akt signaling; theaflavin epigallocatechin; pi3k akt ... See more keywords
(‐)‐Epigallocatechin‐3‐Gallate Antihyperalgesic Effect Associates With Reduced CX3CL1 Chemokine Expression in Spinal Cord
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DOI: 10.1002/ptr.5753
Abstract: (‐)‐Epigallocatechin‐3‐gallate (EGCG) is a major polyphenol in green tea with beneficial effects on the neuropathic pain alleviation in animal models. Because chemokine fractalkine (CX3CL1) has been suggested as an important signal during neuropathic pain development,… read more here.
Keywords: antihyperalgesic effect; egcg treatment; epigallocatechin gallate; expression ... See more keywords
(-)-Epigallocatechin-3-gallate provides neuroprotection via AMPK activation against traumatic brain injury in a mouse model
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01841-1
Abstract: Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. (-)-Epigallocatechin-3-gallate (EGCG) has shown robust neuroprotective effects on various brain injury models in rodents. Herein, we aimed to investigate if EGCG protects… read more here.
Keywords: epigallocatechin gallate; brain injury; injury; traumatic brain ... See more keywords
Epigallocatechin gallate protects against homocysteine-induced vascular smooth muscle cell proliferation
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-017-3142-6
Abstract: Epigallocatechin gallate (EGCG), a bioactive ingredient of green tea, plays a protective role in the cardiovascular system. Homocysteine (Hcy) is a major risk factor for chronic kidney disease and cardiovascular disease. The present study aimed… read more here.
Keywords: vascular smooth; epigallocatechin gallate; proliferation; expression ... See more keywords
Does ( −)-epigallocatechin-3-gallate protect the neurotoxicity induced by bisphenol A in vivo?
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DOI: 10.1007/s11356-021-18408-z
Abstract: Bisphenol A (BPA) is one of the chemicals that is firmly accompanied by hippocampal neuronal injury. As oxidative stress appears to be a major contributor to neurotoxicity induced by BPA, antioxidants with remarkable neuroprotective effects… read more here.
Keywords: neurotoxicity; epigallocatechin gallate; neurotoxicity induced; bpa ... See more keywords
Epigallocatechin gallate and gallic acid affect colonization of abiotic surfaces by oral bacteria.
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DOI: 10.1016/j.archoralbio.2020.104922
Abstract: OBJECTIVES epigallocatechin gallate and gallic acid are known antimicrobial agents. Their roles in controlling microbial colonization, such as bacterial attachment and biofilm formation, are however not completely clear. This study aims to investigate their effects… read more here.
Keywords: gallic acid; oral bacteria; epigallocatechin gallate; colonization ... See more keywords
(-)-Epigallocatechin-3-gallate stimulates myogenic differentiation through TAZ activation.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.03.049
Abstract: Muscle loss is a typical process of aging. Green tea consumption is known to slow down the progress of aging. Their underlying mechanisms, however, remain largely unknown. In this study, we investigated the effect of… read more here.
Keywords: epigallocatechin gallate; differentiation taz; taz; myogenic differentiation ... See more keywords
Antioxidant effects of epigallocatechin-3-gallate on the aTC1-6 pancreatic alpha cell line.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.11.006
Abstract: Hypoglycemia is a major barrier to achieving stable metabolic control in patients with diabetes which is a serious clinical concern. With progression of diabetes, the ability of pancreatic α-cells which respond to hypoglycemia becomes impaired;… read more here.
Keywords: pancreatic alpha; oxidative stress; cell; epigallocatechin gallate ... See more keywords