Epigenetic changes due to physical activity
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1689
Abstract: One of the epigenetic‐modifying factors is regular and continuous physical activity. This article attempts to investigate the effects of physical activity and exercise on changes in histone proteins and gene expression, as well as the… read more here.
Keywords: biochemistry; due physical; epigenetic changes; physical activity ... See more keywords
Dynamic Transcriptional and Epigenetic Changes Drive Cellular Plasticity in the Liver
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31704
Abstract: Following liver injury, a fraction of hepatocytes adopt features of biliary epithelial cells (BECs) in a process known as biliary reprogramming. The aim of this study was to elucidate the molecular events accompanying this dramatic… read more here.
Keywords: dynamic transcriptional; cellular plasticity; changes drive; epigenetic changes ... See more keywords
Triptolide inhibits Wnt signaling in NSCLC through upregulation of multiple Wnt inhibitory factors via epigenetic modifications to Histone H3
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31756
Abstract: In the last decade, it has become clear that epigenetic changes act together with genetic mutations to promote virtually every stage of tumorigenesis and cancer progression. This knowledge has triggered searches for “epigenetic drugs” that… read more here.
Keywords: wnt signaling; epigenetic modifications; wnt inhibitory; epigenetic changes ... See more keywords
Characterizing Epigenetic Changes in Endothelial Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8712-2_23
Abstract: Chromatin immunoprecipitation (ChIP) is an antibody-based method used to identify protein-DNA interactions and sites of protein modifications to chromatin in living cells. ChIP is a powerful method for identifying genomic sites at which epigenetic changes… read more here.
Keywords: changes endothelial; characterizing epigenetic; endothelial cells; epigenetic changes ... See more keywords
Drug Addiction and DNA Modifications.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-53889-1_6
Abstract: Drug addiction is a complex disorder which can be influenced by both genetic and environmental factors. Research has shown that epigenetic modifications can translate environmental signals into changes in gene expression, suggesting that epigenetic changes… read more here.
Keywords: addiction; drug; epigenetic changes; drug addiction ... See more keywords
Epigenetic changes during ageing and their underlying mechanisms
Sign Up to like & getrecommendations! Published in 2020 at "Biogerontology"
DOI: 10.1007/s10522-020-09874-y
Abstract: As life expectancy increases worldwide, ageing and age-related diseases arise as a major issue for societies around the globe. Understanding the biological mechanisms underlying the ageing process is thus instrumental for the development of efficient… read more here.
Keywords: age related; ageing process; age; epigenetic changes ... See more keywords
Relevance of Psychological Symptoms in Pregnancy to Intergenerational Effects of Preconception Trauma
Sign Up to like & getrecommendations! Published in 2018 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2017.10.027
Abstract: Can traumatic experiences occurring before conception influence fetal development? In this issue of Biological Psychiatry, Moog et al. (1) report diminished intracranial volume and cortical gray matter in newborns of mothers exposed to childhood maltreatment,… read more here.
Keywords: preconception; psychological symptoms; trauma; relevance psychological ... See more keywords
The epigenetics of brain tumors and its modulation during radiation: A review.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117974
Abstract: The brain tumor is the abnormal growth of heterogeneous cells around the central nervous system and spinal cord. Most clinically prominent brain tumors affecting both adult and pediatric are glioblastoma, medulloblastoma, and ependymoma and they… read more here.
Keywords: epigenetics brain; review; epigenetic changes; brain ... See more keywords
Social stress, epigenetic changes and pain
Sign Up to like & getrecommendations! Published in 2017 at "Scandinavian Journal of Pain"
DOI: 10.1016/j.sjpain.2017.04.017
Abstract: Abstract Aims Bullying is a prevalent issue in society, with adverse effects ranging from psychological symptoms to somatic ailments like chronic pain. The purpose of this study was to generate new knowledge about the underlying… read more here.
Keywords: social stress; changes pain; stress; pain social ... See more keywords
In vitro transformation of primary human hepatocytes: Epigenetic changes and stemness properties.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2019.111643
Abstract: Human hepatocarcinogenesis is a complex process with many unresolved issues, including the cell of origin (differentiated and/or progenitor/stem cells) and the initial steps leading to tumor development. With the aim of providing new tools for… read more here.
Keywords: stemness; transformation; vitro transformation; epigenetic changes ... See more keywords
SIRT1 reduces epigenetic and non-epigenetic changes to maintain the quality of postovulatory aged oocytes in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112421
Abstract: Postovulatory oocyte aging has a major influence on the development potential of embryos. Many antioxidants can delay oocyte aging by regulating the expression of SIRT1. However, there is a lack of knowledge on SIRT1 function… read more here.
Keywords: sirt1; oocyte aging; postovulatory aged; epigenetic changes ... See more keywords