Abstract NG04: Somatic mutations drive specific but reversible epigenetic heterogeneity states in AML
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DOI: 10.1158/1538-7445.am2020-ng04
Abstract: Cells from the same tumor can exhibit significant variation in their genomes, epigenomes, and transcriptomes, resulting in distinct cellular phenotypes. Such intra-tumor heterogeneity is a substrate for tumor evolution, e.g. generating cell clones with a… read more here.
Keywords: epigenetic clonality; heterogeneity; somatic mutations; reversible epigenetic ... See more keywords