Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19134-9
Abstract: Large portions of eukaryotic genomes consist of transposable elements (TEs), and the establishment of transcription-repressing heterochromatin during early development safeguards genome integrity in Drosophila. Repeat-rich Y chromosomes can act as reservoirs for TEs (‘toxic’ Y… read more here.
Keywords: drosophila; epigenetic conflict; expression; chromosome ... See more keywords
A mobile restriction–modification system provides phage defence and resolves an epigenetic conflict with an antagonistic endonuclease
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac147
Abstract: Abstract Epigenetic DNA methylation plays an important role in bacteria by influencing gene expression and allowing discrimination between self-DNA and intruders such as phages and plasmids. Restriction–modification (RM) systems use a methyltransferase (MTase) to modify… read more here.
Keywords: system; dna; epigenetic conflict; system provides ... See more keywords