Epigenetic crosstalk in chronic infection with HIV-1
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-020-00783-3
Abstract: Human immunodeficiency virus 1 (HIV-1) replicates through the integration of its viral DNA into the genome of human immune target cells. Chronically infected individuals thus carry a genomic burden of virus-derived sequences that persists through… read more here.
Keywords: hiv; infection; epigenetic crosstalk; infection hiv ... See more keywords
A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns
Sign Up to like & getrecommendations! Published in 2021 at "BMC Bioinformatics"
DOI: 10.1186/s12859-021-04272-8
Abstract: Background Epigenetic modifications, including CG methylation (a major form of DNA methylation) and histone modifications, interact with each other to shape their genomic distribution patterns. However, the entire picture of the epigenetic crosstalk regulating the… read more here.
Keywords: methylation; epigenetic crosstalk; model; methylation patterns ... See more keywords
The MOZ-BRPF1 acetyltransferase complex in epigenetic crosstalk linked to gene regulation, development, and human diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1115903
Abstract: Acetylation of lysine residues on histone tails is an important post-translational modification (PTM) that regulates chromatin dynamics to allow gene transcription as well as DNA replication and repair. Histone acetyltransferases (HATs) are often found in… read more here.
Keywords: acetyltransferase; epigenetic crosstalk; acetyltransferase complex; moz brpf1 ... See more keywords