Epigenetic Deregulation in Human Primary Immunodeficiencies.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in immunology"
DOI: 10.1016/j.it.2018.11.005
Abstract: Primary immunodeficiencies (PIDs) are immune disorders resulting from defects in genes involved in immune regulation, and manifesting as an increased susceptibility to infections, autoimmunity, and cancer. However, the molecular basis of some prevalent entities remains… read more here.
Keywords: epigenetic deregulation; deregulation human; primary immunodeficiencies; human primary ... See more keywords
Abstract LB251: Widespread epigenetic deregulation and its dependency on tumor sidedness in colorectal cancer
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-lb251
Abstract: Clinical evidence suggests that right-sided colorectal cancer (CRC) tends to have a worse prognosis compared to left-sided CRC. The distinct functional mechanisms underlying this “sidedness” remain cryptic and poorly understood. Thus, molecular classification of CRC… read more here.
Keywords: colorectal cancer; cancer; crc; deregulation dependency ... See more keywords
Epigenetic Deregulation of Protein Tyrosine Kinase 6 Promotes Carcinogenesis of Oral Squamous Cell Carcinoma
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DOI: 10.3390/ijms23094495
Abstract: Oral squamous cell carcinoma (OSCC) accounts for over 90% of oral cancers and causes considerable morbidity and mortality. Epigenetic deregulation is a common mechanism underlying carcinogenesis. DNA methylation deregulation is the epigenetic change observed during… read more here.
Keywords: cell; methylation; ptk6; deregulation ... See more keywords