DNA methylation variation along the cancer epigenome and the identification of novel epigenetic driver events
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab1167
Abstract: Abstract While large-scale studies applying various statistical approaches have identified hundreds of mutated driver genes across various cancer types, the contribution of epigenetic changes to cancer remains more enigmatic. This is partly due to the… read more here.
Keywords: cancer; epigenetic driver; driver events; dna methylation ... See more keywords
PPARĪ± in the Epigenetic Driver Seat of NAFLD: New Therapeutic Opportunities for Epigenetic Drugs?
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10123041
Abstract: Nonalcoholic fatty liver disease (NAFLD) is a growing epidemic and the most common cause of chronic liver disease worldwide. It consists of a spectrum of liver disorders ranging from simple steatosis to NASH which predisposes… read more here.
Keywords: new therapeutic; ppar; epigenetic drugs; driver seat ... See more keywords