Metabolic and epigenetic dysfunctions underlie the arrest of in vitro fertilized human embryos in a senescent-like state
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DOI: 10.1371/journal.pbio.3001682
Abstract: Around 60% of in vitro fertilized (IVF) human embryos irreversibly arrest before compaction between the 3- to 8-cell stage, posing a significant clinical problem. The mechanisms behind this arrest are unclear. Here, we show that… read more here.
Keywords: epigenetic dysfunctions; like state; metabolic epigenetic; human embryos ... See more keywords