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Published in 2017 at "Nature genetics"
DOI: 10.1038/s41588-017-0034-3
Abstract: Transcription factors (TFs) direct developmental transitions by binding to target DNA sequences, influencing gene expression and establishing complex gene-regultory networks. To systematically determine the molecular components that enable or constrain TF activity, we investigated the…
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Keywords:
genetic determinants;
pioneer factor;
determinants epigenetic;
effects pioneer ... See more keywords
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Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-31822-7
Abstract: The rapid decline in fertility that has been occurring to high-producing dairy cows in the past 50 years seems to be associated with metabolic disturbances such as ketosis, supporting the need for research to improve…
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Keywords:
epigenetic effects;
ketone body;
expression;
body hydroxybutyrate ... See more keywords
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Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4327
Abstract: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental carcinogens formed from the incomplete combustion of organic materials. Exposure to PAHs can be linked to at least 9 different cancer types, including lung and breast cancer. PAH…
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Keywords:
exposure;
benzo pyrene;
epigenetic effects;
cancer ... See more keywords
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Published in 2018 at "American Journal of Health Promotion"
DOI: 10.1177/0890117116661154
Abstract: Purpose: To assess the feasibility of measuring changes in gene expression associated with post-traumatic stress disorder (PTSD) treatment using emotional freedom techniques (EFT). Design: Participants were randomized into an EFT group receiving EFT and treatment…
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Keywords:
intervention;
freedom techniques;
emotional freedom;
epigenetic effects ... See more keywords
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Published in 2019 at "Current Neuropharmacology"
DOI: 10.2174/1570159x17666191010094849
Abstract: An epigenetic effect mainly refers to a heritable modulation in gene expression in the short term but does not involve alterations in the DNA itself. Epigenetic molecular mechanisms include DNA methylation, histone modification, and untranslated…
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Keywords:
application;
epigenetic effects;
effects mediated;
antiepileptic drugs ... See more keywords
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Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1079920
Abstract: Aging is the subject of many studies, facilitating the discovery of many interventions. Epigenetic influences numerous life processes by regulating gene expression and also plays a crucial role in aging regulation. Increasing data suggests that…
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Keywords:
caloric restriction;
restriction;
aging caloric;
restriction induced ... See more keywords
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Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.828055
Abstract: Substance use induces long-lasting behavioral changes and drug craving. Increasing evidence suggests that epigenetic gene regulation contributes to the development and expression of these long-lasting behavioral alterations. Here we systematically review extensive evidence from rodent…
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Keywords:
addictive drugs;
effects addictive;
epigenetic effects;
use ... See more keywords
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Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10061219
Abstract: Infants who are exclusively breastfed in the first six months of age receive adequate nutrients, achieving optimal immune protection and growth. In addition to the known nutritional components of human breast milk (HBM), i.e., water,…
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Keywords:
breast milk;
epigenetic effects;
immunomodulatory properties;
microrna ... See more keywords
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Published in 2017 at "eLife"
DOI: 10.7554/elife.25762
Abstract: Transposable elements (TEs) are widespread genomic parasites, and their evolution has remained a critical question in evolutionary genomics. Here, we study the relatively unexplored epigenetic impacts of TEs and provide the first genome-wide quantification of…
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Keywords:
evolution;
drosophila euchromatic;
epigenetic effects;
pervasive epigenetic ... See more keywords