The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000489917
Abstract: Background/Aims: The epigenetic factor KDM2B is a histone demethylase expressed in various tumors. Recently, we have shown that KDM2B regulates actin cytoskeleton organization, small Rho GTPases signaling, cell-cell adhesion and migration of prostate tumor cells.… read more here.
Keywords: tumor cells; colon tumor; small gtpases; kdm2b ... See more keywords
Meiotic Epigenetic Factor PRDM9 Impacts Sperm Quality of Hybrid Mice.
Sign Up to like & getrecommendations! Published in 2020 at "Reproduction"
DOI: 10.1530/rep-19-0528
Abstract: Reduced fertility of male mouse hybrids relative to their parents, or hybrid sterility, is governed by the hybrid sterility 1 (Hst1) locus. Rescue experiments with transgenes carrying sequences within or near Hst1 manifested that Hst1… read more here.
Keywords: sperm quality; meiotic epigenetic; epigenetic factor; factor prdm9 ... See more keywords
An epigenetic master regulator teams up to become an epioncogene
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16484
Abstract: Genomics has changed the way we diagnose and treat cancer [1]. Our ability to map our own genes (Figure 1A) will be a bigger part of medical care in the future. But perception, value, and… read more here.
Keywords: gene; cancer; factor; transcription factors ... See more keywords