Articles with "epigenetic features" as a keyword



Improved simultaneous mapping of epigenetic features and 3D chromatin structure via ViCAR

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Published in 2024 at "Genome Biology"

DOI: 10.1186/s13059-024-03377-6

Abstract: Methods to measure chromatin contacts at genomic regions bound by histone modifications or proteins are important tools to investigate chromatin organization. However, such methods do not capture the possible involvement of other epigenomic features such… read more here.

Keywords: improved simultaneous; simultaneous mapping; epigenetic features; mapping epigenetic ... See more keywords

Machine learning on multiple epigenetic features reveals H3K27Ac as a driver of gene expression prediction across patients with glioblastoma

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Published in 2025 at "PLOS Computational Biology"

DOI: 10.1371/journal.pcbi.1012272

Abstract: Epigenetic mechanisms play a crucial role in driving transcript expression and shaping the phenotypic plasticity of glioblastoma stem cells (GSCs), contributing to tumor heterogeneity and therapeutic resistance. These mechanisms dynamically regulate the expression of key… read more here.

Keywords: gene expression; epigenetic features; biology; machine learning ... See more keywords
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Hepatocarcinoma: genetic and epigenetic features.

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Published in 2018 at "Minerva gastroenterologica e dietologica"

DOI: 10.23736/s1121-421x.17.02408-4

Abstract: HCC is the third leading cause of cancer-related deaths worldwide, accounting for about 1 million deaths annually. The incidence of HCC is highest in Asia and Africa, where the endemic high prevalence of hepatitis B… read more here.

Keywords: genetic epigenetic; epigenetic features; hcc; hepatocarcinoma genetic ... See more keywords

Epigenetic Features of HIV-Induced T-Cell Exhaustion Persist Despite Early Antiretroviral Therapy

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.647688

Abstract: T cell dysfunction occurs early following HIV infection, impacting the emergence of non-AIDS morbidities and limiting curative efforts. ART initiated during primary HIV infection (PHI) can reverse this dysfunction, but the extent of recovery is… read more here.

Keywords: phi; hiv infection; cell; epigenetic features ... See more keywords

Unique Epigenetic Features of Ribosomal RNA Genes (rDNA) in Early Diverging Plants (Bryophytes)

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Published in 2019 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2019.01066

Abstract: Introduction: In plants, the multicopy genes encoding ribosomal RNA (rDNA) typically exhibit heterochromatic features and high level of DNA methylation. Here, we explored rDNA methylation in early diverging land plants from Bryophyta (15 species, 14… read more here.

Keywords: methylation; seed; ribosomal rna; early diverging ... See more keywords

Characterization of Expression and Epigenetic Features of Core Genes in Common Wheat

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Published in 2022 at "Genes"

DOI: 10.3390/genes13071112

Abstract: The availability of multiple wheat genome sequences enables us to identify core genes and characterize their genetic and epigenetic features, thereby advancing our understanding of their biological implications within individual plant species. It is, however,… read more here.

Keywords: wheat; expression; core genes; epigenetic features ... See more keywords