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Published in 2024 at "Genome Biology"
DOI: 10.1186/s13059-024-03377-6
Abstract: Methods to measure chromatin contacts at genomic regions bound by histone modifications or proteins are important tools to investigate chromatin organization. However, such methods do not capture the possible involvement of other epigenomic features such…
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Keywords:
improved simultaneous;
simultaneous mapping;
epigenetic features;
mapping epigenetic ... See more keywords
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Published in 2025 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1012272
Abstract: Epigenetic mechanisms play a crucial role in driving transcript expression and shaping the phenotypic plasticity of glioblastoma stem cells (GSCs), contributing to tumor heterogeneity and therapeutic resistance. These mechanisms dynamically regulate the expression of key…
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Keywords:
gene expression;
epigenetic features;
biology;
machine learning ... See more keywords
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Published in 2018 at "Minerva gastroenterologica e dietologica"
DOI: 10.23736/s1121-421x.17.02408-4
Abstract: HCC is the third leading cause of cancer-related deaths worldwide, accounting for about 1 million deaths annually. The incidence of HCC is highest in Asia and Africa, where the endemic high prevalence of hepatitis B…
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Keywords:
genetic epigenetic;
epigenetic features;
hcc;
hepatocarcinoma genetic ... See more keywords
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Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.647688
Abstract: T cell dysfunction occurs early following HIV infection, impacting the emergence of non-AIDS morbidities and limiting curative efforts. ART initiated during primary HIV infection (PHI) can reverse this dysfunction, but the extent of recovery is…
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Keywords:
phi;
hiv infection;
cell;
epigenetic features ... See more keywords
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Published in 2019 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2019.01066
Abstract: Introduction: In plants, the multicopy genes encoding ribosomal RNA (rDNA) typically exhibit heterochromatic features and high level of DNA methylation. Here, we explored rDNA methylation in early diverging land plants from Bryophyta (15 species, 14…
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Keywords:
methylation;
seed;
ribosomal rna;
early diverging ... See more keywords
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Published in 2022 at "Genes"
DOI: 10.3390/genes13071112
Abstract: The availability of multiple wheat genome sequences enables us to identify core genes and characterize their genetic and epigenetic features, thereby advancing our understanding of their biological implications within individual plant species. It is, however,…
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Keywords:
wheat;
expression;
core genes;
epigenetic features ... See more keywords