Noncoding RNA and epigenetic gene regulation in renal diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Drug discovery today"
DOI: 10.1016/j.drudis.2017.04.020
Abstract: Kidneys have a major role in normal physiology and metabolic homeostasis. Loss or impairment of kidney function is a common occurrence in several metabolic disorders, including hypertension and diabetes. Chronic kidney disease (CKD) affect nearly… read more here.
Keywords: gene regulation; epigenetic gene; noncoding rna; renal diseases ... See more keywords
An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydomonas
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DOI: 10.1038/s41467-020-19983-4
Abstract: Silencing of exogenous DNA can make transgene expression very inefficient. Genetic screens in the model alga Chlamydomonas have demonstrated that transgene silencing can be overcome by mutations in unknown gene(s), thus producing algal strains that… read more here.
Keywords: silencing pathway; transgenic dna; dna; epigenetic gene ... See more keywords