Articles with "epigenetic immunomodulator" as a keyword



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The epigenetic immunomodulator, HBI-8000, enhances the response and reverses resistance to checkpoint inhibitors

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Published in 2021 at "BMC Cancer"

DOI: 10.1186/s12885-021-08702-x

Abstract: Background Treatment with immune checkpoint inhibitors (ICIs) targeting CTLA-4 and the PD-1/PD-L1 axis is effective against many cancer types. However, due in part to unresponsiveness or acquired resistance, not all patients experience a durable response… read more here.

Keywords: checkpoint inhibitors; hbi; epigenetic immunomodulator; hbi 8000 ... See more keywords