Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
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DOI: 10.1016/j.ajhg.2021.03.005
Abstract: The fetal-to-adult hemoglobin switch is regulated in a developmental stage-specific manner and reactivation of fetal hemoglobin (HbF) has therapeutic implications for treatment of β-thalassemia and sickle cell anemia, two major global health problems. Although significant… read more here.
Keywords: hbf; erf; epigenetic inactivation; thalassemia ... See more keywords