Epigenetic Landscape Changes Due to Acupuncture Treatment: From Clinical to Basic Research
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-020-2852-x
Abstract: Acupuncture has been widely used for treating diseases since the ancient days in China, but the mechanism by which acupuncture exerts such powerful roles is unclear. Epigenetics, including DNA methylation, histone modification, and post-transcriptional regulation… read more here.
Keywords: research; acupuncture; epigenetic landscape; mechanism acupuncture ... See more keywords
Survey of the Arc Epigenetic Landscape in Normal Cognitive Aging
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01915-4
Abstract: Aging is accompanied by aberrant gene expression that ultimately affects brain plasticity and the capacity to form long-term memories. Immediate-early genes (IEGs) play an active role in these processes. Using a rat model of normal… read more here.
Keywords: epigenetic landscape; cognitive aging; expression; arc epigenetic ... See more keywords
When function follows form: Nuclear compartment structure and the epigenetic landscape of the aging neuron
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2020.110876
Abstract: The human brain is heavily affected by cellular aging. Neurons are primarily generated during embryogenesis and early life with a limited capacity for renewal and replacement, making them some of the oldest cells in the… read more here.
Keywords: form nuclear; epigenetic landscape; landscape; function follows ... See more keywords
Exercise, redox homeostasis and the epigenetic landscape
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101477
Abstract: Physical exercise represents one of the strongest physiological stimuli capable to induce functional and structural modifications in all biological systems. Indeed, beside the traditional genetic mechanisms, physical exercise can modulate gene expression through epigenetic modifications,… read more here.
Keywords: redox homeostasis; homeostasis epigenetic; exercise redox; epigenetic landscape ... See more keywords
P5435Epigenetic modifications and gene expressions in Mybpc3 knockout mice
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz746.0391
Abstract: DNA methylation and hydroxymethylation plays critical role in important biological processes, including differentiation of tissues in the embryo and cellular response to different diseases and diverse environmental factors. The epigenetic landscape in heart failure might… read more here.
Keywords: gene expression; epigenetic landscape; knockout mice; mice ... See more keywords
Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape
Sign Up to like & getrecommendations! Published in 2017 at "Aging Cell"
DOI: 10.1111/acel.12621
Abstract: Ideally, disease modeling using patient‐derived induced pluripotent stem cells (iPSCs) enables analysis of disease initiation and progression. This requires any pathological features of the patient cells used for reprogramming to be eliminated during iPSC generation.… read more here.
Keywords: reprogramming progeria; initiation progression; epigenetic landscape; landscape ... See more keywords
The epigenetic landscape of oligodendrocyte lineage cells
Sign Up to like & getrecommendations! Published in 2023 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14959
Abstract: The epigenetic landscape of oligodendrocyte lineage cells refers to the cell‐specific modifications of DNA, chromatin, and RNA that define a unique gene expression pattern of functionally specialized cells. Here, we focus on the epigenetic changes… read more here.
Keywords: oligodendrocyte lineage; epigenetic landscape; landscape oligodendrocyte; lineage ... See more keywords
Recycling of parental histones preserves the epigenetic landscape during embryonic development
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.add6440
Abstract: Epigenetic inheritance during DNA replication requires an orchestrated assembly of nucleosomes from parental and newly synthesized histones. We analyzed Drosophila HisC mutant embryos harboring a deletion of all canonical histone genes, in which nucleosome assembly… read more here.
Keywords: epigenetic landscape; histones preserves; parental histones; recycling parental ... See more keywords
Cooperative Instruction of Signaling and Metabolic Pathways on the Epigenetic Landscape
Sign Up to like & getrecommendations! Published in 2018 at "Molecules and Cells"
DOI: 10.14348/molcells.2018.0076
Abstract: Cells cope with diverse intrinsic and extrinsic stimuli in order to make adaptations for survival. The epigenetic landscape plays a crucial role in cellular adaptation, as it integrates the information generated from stimuli. Signaling pathways… read more here.
Keywords: instruction signaling; metabolic pathways; epigenetic landscape; landscape ... See more keywords
Implications of Transglutaminase-Mediated Protein Serotonylation in the Epigenetic Landscape, Small Cell Lung Cancer, and Beyond
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15041332
Abstract: Simple Summary From the landmark report of protein serotonylation on small GTPases in 2003 to the most recent discovery of serotonin-modified histone H3 leading to epigenetic changes, over the course of the past 20 years,… read more here.
Keywords: epigenetic landscape; histone; protein serotonylation; cancer ... See more keywords
Comprehensive characterization of the epigenetic landscape in Multiple Myeloma
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.54453
Abstract: Background: Human multiple myeloma (MM) cell lines (HMCLs) have been widely used to understand the molecular processes that drive MM biology. Epigenetic modifications are involved in MM development, progression, and drug resistance. A comprehensive characterization… read more here.
Keywords: histone; comprehensive characterization; multiple myeloma; biology ... See more keywords