Novel epigenetic link between gestational diabetes mellitus and macrosomia.
Sign Up to like & getrecommendations! Published in 2021 at "Epigenomics"
DOI: 10.2217/epi-2021-0096
Abstract: Background & objectives: Examine maternal gestational diabetes mellitus (GDM), macrosomia and DNA methylation in candidate genes IGF1, IGF2, H19, ARHGRF11, MEST, NR3C1, ADIPOQ and RETN. Materials & methods: 1145 Children (572 GDM cases and 573 controls) from The Tianjin… read more here.
Keywords: gestational diabetes; epigenetic link; diabetes mellitus; link gestational ... See more keywords
Metformin: Targeting the Metabolo-Epigenetic Link in Cancer Biology
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.620641
Abstract: Metabolism can directly drive or indirectly enable an aberrant chromatin state of cancer cells. The physiological and molecular principles of the metabolic link to epigenetics provide a basis for pharmacological modulation with the anti-diabetic biguanide… read more here.
Keywords: metformin; epigenetic link; metabolo epigenetic; biology ... See more keywords