Epigenetic manipulation of filamentous fungi for biotechnological applications: a systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Letters"
DOI: 10.1007/s10529-020-02871-8
Abstract: The study of the epigenetic regulation of gene function has reached pivotal importance in life sciences in the last decades. The mechanisms and effects of processes such as DNA methylation, histone posttranslational modifications and non-coding… read more here.
Keywords: biotechnological applications; filamentous fungi; epigenetic manipulation; manipulation filamentous ... See more keywords
Epigenetic Manipulation to Trigger Production of Guaiane-Type Sesquiterpenes from a Marine-Derived Spiromastix sp. Fungus with Antineuroinflammatory Effects.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.1c00293
Abstract: Epigenetic manipulation of a deep-sea sediment-derived Spiromastix sp. fungus using suberoylanilide hydroxamic acid (SAHA) induction resulted in the activation of a terpene-related biosynthetic gene cluster, and nine new guaiane-type sesquiterpenes, spiromaterpenes A-I (1-9), were isolated.… read more here.
Keywords: guaiane; epigenetic manipulation; spiromastix fungus; derived spiromastix ... See more keywords
Three new ɑ-pyrone derivatives induced by chemical epigenetic manipulation of Penicillium herquei, an endophytic fungus isolated from Cordyceps sinensis
Sign Up to like & getrecommendations! Published in 2019 at "Natural Product Research"
DOI: 10.1080/14786419.2018.1544974
Abstract: Abstract Chemical epigenetic manipulation was applied to explore secondary metabolite of an endophytic fungus Penicillium herquei, which was obtained from the fruiting body of Cordyceps sinensis, and three previously undescribed polyketides with pyran-2-one scaffold were… read more here.
Keywords: chemical epigenetic; endophytic fungus; epigenetic manipulation; cordyceps sinensis ... See more keywords
New butanolide derivatives from the marine derived fungus Aspergillus terreus GZU-31-1 by chemical epigenetic manipulation.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2140338
Abstract: Chemical epigenetic manipulation of Aspergillus terreus GZU-31-1 led to the discovery of five butanolide derivatives (1-5), including two new ones (1 and 2), and four known diphenyl ether derivatives (6-9). Compound 1 featured a Z-configuration… read more here.
Keywords: epigenetic manipulation; butanolide derivatives; chemical epigenetic; aspergillus terreus ... See more keywords
Epigenetic Manipulation of Psychiatric Behavioral Disorders Induced by Toxoplasma gondii
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.803502
Abstract: Toxoplasma gondii is known to have a complex life cycle and infect almost all kinds of warm-blooded animals around the world. The brain of the host could be persistently infected by cerebral cysts, and a… read more here.
Keywords: epigenetic manipulation; behavioral disorders; manipulation; disorders induced ... See more keywords
Epigenetic manipulation to improve mouse SCNT embryonic development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.932867
Abstract: Cloned mammals can be achieved through somatic cell nuclear transfer (SCNT), which involves reprogramming of differentiated somatic cells into a totipotent state. However, low cloning efficiency hampers its application severely. Cloned embryos have the same… read more here.
Keywords: epigenetic manipulation; development; mouse scnt; improve mouse ... See more keywords
Epigenetic Manipulation Induced Production of Immunosuppressive Chromones and Cytochalasins from the Mangrove Endophytic Fungus Phomopsis asparagi DHS-48
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DOI: 10.3390/md20100616
Abstract: A mangrove endophytic fungus Phomopsis asparagi DHS-48 was found to be particularly productive with regard to the accumulation of substantial new compounds in our previous study. In order to explore its potential to produce more… read more here.
Keywords: epigenetic manipulation; phomopsis asparagi; mangrove endophytic; endophytic fungus ... See more keywords