Chromatinâassociated noncoding RNAs in development and inheritance
Sign Up to like & getrecommendations! Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1435
Abstract: Noncoding RNAs (ncRNAs) have emerged as crucial players in chromatin regulation. Their diversity allows them to partake in the regulation of numerous cellular processes across species. During development, long and short ncRNAs act in conjunction… read more here.
Keywords: epigenetic marks; inheritance; chromatin associated; noncoding rnas ... See more keywords
A Hypothesis: Retrotransposons as a Relay of Epigenetic Marks in Intergenerational Epigenetic Inheritance.
Sign Up to like & getrecommendations! Published in 2022 at "Gene"
DOI: 10.1016/j.gene.2022.146229
Abstract: Epigenetic marks in gametes, which both respond to the parental environmental factors and shape offspring phenotypes, are usually positioned to mediate intergenerational or transgenerational epigenetic inheritance. Nonetheless, the mechanisms through which gametic epigenetic signatures encode… read more here.
Keywords: epigenetic inheritance; embryonic development; early embryonic; gametic epigenetic ... See more keywords
Stress affects the epigenetic marks added by natural transposable element insertions in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-30491-w
Abstract: Transposable elements are emerging as an important source of cis-acting regulatory sequences and epigenetic marks that could influence gene expression. However, few studies have dissected the role of specific transposable element insertions on epigenetic gene… read more here.
Keywords: epigenetic marks; transposable element; bari jheh; element insertions ... See more keywords
Exploring epigenetic reprogramming during central nervous system infection
Sign Up to like & getrecommendations! Published in 2022 at "Immunological Reviews"
DOI: 10.1111/imr.13079
Abstract: Epigenetics involves the study of various modes of adaptable transcriptional regulation, contributing to cell identity, characteristics, and function. During central nervous system (CNS) infection, epigenetic mechanisms can exert pronounced control over the maturation and antimicrobial… read more here.
Keywords: exploring epigenetic; central nervous; infection; nervous system ... See more keywords
Abstract 4718: Analyses of epigenetic marks and mechanisms in disease: Your guide to a successful CUT&RUN assay
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4718
Abstract: Like the chromatin immunoprecipitation (ChIP) assay, Cleavage Under Targets & Release Using Nuclease (CUT&RUN) is a powerful and versatile technique used for probing protein-DNA interactions within the natural chromatin context of the cell. The CUT&RUN… read more here.
Keywords: analyses epigenetic; cut; cut run; marks mechanisms ... See more keywords
Epigenetic marks in Polycystic Ovary Syndrome.
Sign Up to like & getrecommendations! Published in 2019 at "Current medicinal chemistry"
DOI: 10.2174/0929867326666191003154548
Abstract: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder that affects women in their reproductive age. Recent studies have shown that genes have an important role in the etiology of PCOS. However, the… read more here.
Keywords: epigenetic marks; marks polycystic; polycystic ovary; pcos ... See more keywords
A Review on CRISPR-Mediated Epigenome Editing: A Future Directive for Therapeutic Management of Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug targets"
DOI: 10.2174/1389450123666220117105531
Abstract: Recent studies have shed light on the role of epigenetic marks in certain diseases like cancer, type II diabetes mellitus (T2DM), obesity, and cardiovascular dysfunction, to name a few. Epigenetic marks like DNA methylation and… read more here.
Keywords: crispr; mediated epigenome; crispr mediated; review crispr ... See more keywords
Abnormal Epigenetic Regulation of Immune System during Aging
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00197
Abstract: Epigenetics refers to the study of mechanisms controlling the chromatin structure, which has fundamental role in the regulation of gene expression and genome stability. Epigenetic marks, such as DNA methylation and histone modifications, are established… read more here.
Keywords: immune; epigenetic marks; abnormal epigenetic; function ... See more keywords
Chromatin Manipulation and Editing: Challenges, New Technologies and Their Use in Plants
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22020512
Abstract: An ongoing challenge in functional epigenomics is to develop tools for precise manipulation of epigenetic marks. These tools would allow moving from correlation-based to causal-based findings, a necessary step to reach conclusions on mechanistic principles.… read more here.
Keywords: epigenetic marks; editing challenges; challenges new; chromatin manipulation ... See more keywords
Targeting the epigenome to treat neurodegenerative diseases or delay their onset: a perspective
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.332145
Abstract: Epigenetic mechanisms regulate the chromatin structure and gene expression levels without changing the primary D N A s e q u e n c e , a n d i n c l u d… read more here.
Keywords: targeting epigenome; creighton 2020; epigenome treat; gene ... See more keywords