Fructose-mediated effects on gene expression and epigenetic mechanisms associated with NAFLD pathogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03390-0
Abstract: Nonalcoholic fatty liver disease (NAFLD) is a chronic, frequently progressive condition that develops in response to excessive hepatocyte fat accumulation (i.e., steatosis) in the absence of significant alcohol consumption. Liver steatosis develops as a result… read more here.
Keywords: dietary fructose; pathogenesis; epigenetic mechanisms; expression ... See more keywords
p38 МАРK is Involved in Regulation of Epigenetic Mechanisms of Food Aversion Learning
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3816-9
Abstract: Consolidation of the conditioned food aversion response in Helix lucorum was associated with induction of histone H3 acetylation and methylation. We hypothesized that not only activatory, but also inhibitory p38 MARK-mediated pathways are involved in… read more here.
Keywords: epigenetic mechanisms; regulation epigenetic; food aversion; involved regulation ... See more keywords
Epigenetic mechanisms of alcoholism and stress-related disorders.
Sign Up to like & getrecommendations! Published in 2017 at "Alcohol"
DOI: 10.1016/j.alcohol.2017.01.001
Abstract: Stress-related disorders, such as anxiety, early life stress, and posttraumatic stress disorder appear to be important factors in promoting alcoholism, as alcohol consumption can temporarily attenuate the negative affective symptoms of these disorders. Several molecules… read more here.
Keywords: alcoholism; stress related; epigenetic mechanisms; stress ... See more keywords
Epigenetic mechanisms in odontogenic tumors: A literature review.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2017.12.029
Abstract: OBJECTIVE Epigenetic mechanisms, such as DNA methylation, regulate important biological processes as gene expression and it was suggested that these phenomena play important roles in the carcinogenesis and tumor biology. The aim of this review… read more here.
Keywords: odontogenic tumors; epigenetic mechanisms; non coding; biology ... See more keywords
Epigenetic mechanisms underlying the therapeutic effects of HDAC inhibitors in chronic myeloid leukemia.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.113698
Abstract: Chronic myeloid leukemia (CML) is a hematological disorder caused by the oncogenic BCR-ABL fusion protein in more than 90% of patients. Despite the striking improvements in the management of CML patients since the introduction of… read more here.
Keywords: epigenetic mechanisms; myeloid leukemia; chronic myeloid; mechanisms underlying ... See more keywords
Epigenetic Mechanisms in Drug Relapse
Sign Up to like & getrecommendations! Published in 2021 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2020.08.005
Abstract: A growing body of evidence from the past 15 years implicates epigenetic mechanisms in the behavioral effects of addictive drugs. The main focus of these studies has been epigenetic mechanisms of psychomotor sensitization and drug… read more here.
Keywords: self administration; drug; relapse; epigenetic mechanisms ... See more keywords
Epigenetic mechanisms driving lineage commitment in mesenchymal stem cells.
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115309
Abstract: The increasing application of approaches that allow tracing of individual cells over time, together with transcriptomics and epigenomics analyses is changing the way resident stromal stem cells (mesenchymal stem cells) are viewed. Rather than being… read more here.
Keywords: driving lineage; epigenetic mechanisms; stem; stem cells ... See more keywords
Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.10.010
Abstract: Genomic imprinting and X chromosome inactivation (XCI) require epigenetic mechanisms to encode allele-specific expression, but how these specific tasks are accomplished at single loci or across chromosomal scales remains incompletely understood. Here, we systematically disrupt… read more here.
Keywords: mechanisms maintain; diverse epigenetic; parental imprints; epigenetic mechanisms ... See more keywords
Identification of epigenetic mechanisms in paddy crop associated with lowering environmentally related cadmium risks to food safety.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental pollution"
DOI: 10.1016/j.envpol.2019.113464
Abstract: Cadmium (Cd) is a toxic metal that contributes to human diseases such as pediatric cancer and cardiovascular dysfunction. Epigenetic modification caused by Cd exposure is the major factor in etiology of environmentally-relevant diseases. However, the… read more here.
Keywords: identification epigenetic; epigenetic mechanisms; cadmium; mechanisms paddy ... See more keywords
Epigenetic mechanisms of macrophage activation in type 2 diabetes.
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DOI: 10.1016/j.imbio.2016.08.011
Abstract: The alarming rise of obesity and type 2 diabetes (T2D) has put a tremendous strain on global healthcare systems. Over the past decade extensive research has focused on the role of macrophages as key mediators… read more here.
Keywords: epigenetic mechanisms; type diabetes; macrophage; macrophage activation ... See more keywords
Epigenetic dysregulation in chronic myeloid leukaemia: A myriad of mechanisms and therapeutic options.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2017.07.006
Abstract: The onset of global epigenetic changes in chromatin that drive tumor proliferation and heterogeneity is a hallmark of many forms of cancer. Identifying the epigenetic mechanisms that govern these changes and developing therapeutic approaches to… read more here.
Keywords: cml; epigenetic mechanisms; dysregulation chronic; chronic myeloid ... See more keywords