Development and application of novel BiFC probes for cell sorting based on epigenetic modification
Sign Up to like & getrecommendations! Published in 2022 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24530
Abstract: The epigenetic signature of cancer cells varies with disease progression and drug treatment, necessitating the study of these modifications with single cell resolution over time. The rapid detection and sorting of cells based on their… read more here.
Keywords: application; development; application novel; based epigenetic ... See more keywords
Cross Talk Between Aluminum and Genetic Susceptibility and Epigenetic Modification in Alzheimer's Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-1370-7_10
Abstract: This chapter primarily focuses on two key aspects related to aluminum neurotoxicity and its mechanism in Alzheimer's disease (AD), which are genetic susceptibility and epigenetic modification. The toxicity of aluminum has been confirmed from plant… read more here.
Keywords: alzheimer disease; epigenetic modification; genetic susceptibility; susceptibility epigenetic ... See more keywords
Influence of psychostimulants and opioids on epigenetic modification of class III histone deacetylase (HDAC)-sirtuins in glial cells
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-00836-z
Abstract: Substance abuse affects the central nervous system (CNS) and remains a global health problem. Psychostimulants, such as cocaine and methamphetamine (METH), and opioids affect neuronal function and lead to behavioral impairments via epigenetic modification. Epigenetic… read more here.
Keywords: epigenetic modification; class; iii histone; class iii ... See more keywords
Sulforaphane prevents angiotensin II‐induced cardiomyopathy by activation of Nrf2 through epigenetic modification
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16504
Abstract: Nuclear factor erythroid 2‐related factor (Nrf2) is an important regulator of cellular antioxidant defence. We previously showed that SFN prevented Ang II‐induced cardiac damage via activation of Nrf2. However, the underlying mechanism of SFN’s persistent… read more here.
Keywords: epigenetic modification; ang induced; nrf2 epigenetic; activation nrf2 ... See more keywords
Epigenetic Modification of Enhancer of Zeste Homolog 2 Modulates the Activation of Dendritic Cells in Allergen Immunotherapy
Sign Up to like & getrecommendations! Published in 2019 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000500882
Abstract: Background: Allergen immunotherapy (AIT) is the only etiological and potentially curative therapy for allergic rhinitis (AR). Objectives: We sought to investigate the role of epigenetic regulator enhancer of zeste homolog 2 (EZH2) in the activation… read more here.
Keywords: epigenetic modification; allergen immunotherapy; zeste homolog; activation dendritic ... See more keywords
Epigenetic modification, co-culture and genomic methods for natural product discovery
Sign Up to like & getrecommendations! Published in 2018 at "Physical Sciences Reviews"
DOI: 10.1515/psr-2018-0118
Abstract: Abstract Fungi and bacteria are encountered in many habitats where they live in complex communities interacting with one another mainly by producing secondary metabolites, which are organic compounds that are not directly involved in the… read more here.
Keywords: epigenetic modification; medicine; modification culture; discovery ... See more keywords
Epigenetic Modification in Macrophages: A Promising Target for Tumor and Inflammation-associated Disease Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026619666190619143706
Abstract: Macrophages are essential for supporting tissue homeostasis, regulating immune response, and promoting tumor progression. Due to its heterogeneity, macrophages have different phenotypes and functions in various tissues and diseases. It is becoming clear that epigenetic… read more here.
Keywords: modification macrophages; epigenetic modification; inflammation associated; tumor ... See more keywords
Multiple epigenetic modification profiles reveal the tumor immune microenvironment and clinical outcomes of uveal melanoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1155199
Abstract: Uveal melanoma (UM) is an aggressive intraocular cancer that, in 50% of cases, spreads to the patient’s other systems. The exact cause of the increased metastatic rate is still unknown. Methylation and immune response, metastasis,… read more here.
Keywords: prognosis; epigenetic modification; multiple epigenetic; immune ... See more keywords
Epigenetic modification-related mechanisms of hepatocellular carcinoma resistance to immune checkpoint inhibition
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1043667
Abstract: Hepatocellular carcinoma (HCC) constitutes most primary liver cancers and is one of the most lethal and life-threatening malignancies globally. Unfortunately, a substantial proportion of HCC patients are identified at an advanced stage that is unavailable… read more here.
Keywords: hepatocellular carcinoma; resistance; epigenetic modification; immune checkpoint ... See more keywords
Development and Validation of Epigenetic Modification-Related Signals for the Diagnosis and Prognosis of Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.649093
Abstract: Background Increasing evidence has indicated that abnormal epigenetic factors such as RNA m6A modification, histone modification, DNA methylation, RNA binding proteins and transcription factors are correlated with hepatocarcinogenesis. However, it is unknown how epigenetic modification-associated… read more here.
Keywords: epigenetic modification; hcc; modification associated; prognosis ... See more keywords
Editorial: Altered epigenetic modification mediated dysregulated transcriptional networks in drug resistance
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1196448
Abstract: COPYRIGHT © 2023 Brunetti and Yoshida. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the… read more here.
Keywords: editorial; editorial altered; mediated dysregulated; epigenetic modification ... See more keywords