Epigenetics across the evolutionary tree: New paradigms from non‐model animals
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DOI: 10.1002/bies.202200036
Abstract: All animals have evolved solutions to manage their genomes, enabling the efficient organization of meters of DNA strands in the nucleus and allowing for nuanced regulation of gene expression while keeping transposable elements suppressed. Epigenetic… read more here.
Keywords: evolutionary tree; epigenetics across; across evolutionary; epigenetic modifications ... See more keywords
Erratum for “Advances in mapping the epigenetic modifications of 5‐methylcytosine (5mC), N6‐methyladenine (6mA), and N4‐methylcytosine (4mC)” (Vol. 118, Issue 11, pp. 4204–4216)
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28042
Abstract: Biotechnol Bioeng. 2022;119:1171. wileyonlinelibrary.com/journal/bit © 2022 Wiley Periodicals LLC | 1171 On page 4208, the text “TAPS uses a standard modification‐ calling tool called asTair (H. Li & Durbin, 2009),” should read “TAPS uses a… read more here.
Keywords: mapping epigenetic; erratum advances; methylcytosine 5mc; modifications methylcytosine ... See more keywords
Triptolide inhibits Wnt signaling in NSCLC through upregulation of multiple Wnt inhibitory factors via epigenetic modifications to Histone H3
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DOI: 10.1002/ijc.31756
Abstract: In the last decade, it has become clear that epigenetic changes act together with genetic mutations to promote virtually every stage of tumorigenesis and cancer progression. This knowledge has triggered searches for “epigenetic drugs” that… read more here.
Keywords: wnt signaling; epigenetic modifications; wnt inhibitory; epigenetic changes ... See more keywords
Epigenetic modifications in chronic myeloid leukemia cells through ruxolitinib treatment
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DOI: 10.1002/jcb.27744
Abstract: Chronic myeloid leukemia is a clonal malignancy of hematopoietic stem cell that is characterized by the occurrence of t(9;22)(q34;q11.2) translocation, named Philadelphia chromosome. Ruxolitinib is a powerful Janus tyrosine kinase 1 and 2 inhibitor that… read more here.
Keywords: epigenetic modifications; ruxolitinib treatment; cells ruxolitinib; myeloid leukemia ... See more keywords
Intracellular matrix metalloproteinase‐9 mediates epigenetic modifications and autophagy to regulate differentiation in human cardiac stem cells
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DOI: 10.1002/stem.3330
Abstract: Epigenetic reprogramming and autophagy have critical roles in differentiation of stem cells. However, very little is known about how epigenetic modifications are mediated and how they contribute to autophagy and differentiation in human cardiac stem… read more here.
Keywords: epigenetic modifications; hcscs; differentiation; modifications autophagy ... See more keywords
Epigenetics and the Environment in Airway Disease: Asthma and Allergic Rhinitis.
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DOI: 10.1007/978-981-15-3449-2_6
Abstract: Asthma and rhinitis are complex, heterogeneous diseases characterized by chronic inflammation of the upper and lower airways. While genome-wide association studies (GWAS) have identified a number of susceptible loci and candidate genes associated with the… read more here.
Keywords: allergic rhinitis; airway disease; rhinitis; epigenetic modifications ... See more keywords
Epigenetic modifications of Klotho expression in kidney diseases.
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DOI: 10.1007/s00109-021-02044-8
Abstract: Developments of many renal diseases are substantially influenced by epigenetic modifications of numerous genes, mainly mediated by DNA methylations, histone modifications, and microRNA interference; however, not all gene modifications causally affect the disease onset or… read more here.
Keywords: modifications klotho; epigenetic modifications; kidney diseases; expression kidney ... See more keywords
The Essential Role of Epigenetic Modifications in Neurodegenerative Diseases with Dyskinesia.
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DOI: 10.1007/s10571-021-01133-z
Abstract: Epigenetics play an essential role in the occurrence and improvement of many diseases. Evidence shows that epigenetic modifications are crucial to the regulation of gene expression. DNA methylation is closely linked to embryonic development in… read more here.
Keywords: epigenetic modifications; modifications neurodegenerative; essential role; neurodegenerative diseases ... See more keywords
Epigenetic Markers and Microbiota/Metabolite-Induced Epigenetic Modifications in the Pathogenesis of Obesity, Metabolic Syndrome, Type 2 Diabetes, and Non-alcoholic Fatty Liver Disease
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DOI: 10.1007/s11892-019-1151-4
Abstract: Purpose of ReviewThe metabolic syndrome is a pathological state in which one of the key components is insulin resistance. A wide spectrum of body compartments is involved in its pathophysiology. Genetic and environmental factors such… read more here.
Keywords: induced epigenetic; epigenetic modifications; non alcoholic; disease ... See more keywords
Epigenetic modifications of gene expression by lifestyle and environment
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DOI: 10.1007/s12272-017-0973-3
Abstract: Epigenetics oftenly described as the heritable changes in gene expression independent of changes in DNA sequence. Various environmental factors such as nutrition-dietary components, lifestyle, exercise, physical activity, toxins, and other contributing factors remodel the genome… read more here.
Keywords: epigenetic modifications; dna; gene expression; modifications gene ... See more keywords
Mapping the epigenetic modifications of DNA and RNA
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DOI: 10.1007/s13238-020-00733-7
Abstract: Over 17 and 160 types of chemical modifications have been identified in DNA and RNA, respectively. The interest in understanding the various biological functions of DNA and RNA modifications has lead to the cutting-edged fields… read more here.
Keywords: modifications dna; mapping epigenetic; dna rna; epigenetic modifications ... See more keywords