Epigenetic modulation in chronic hepatitis B virus infection
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-020-00780-6
Abstract: The human hepatitis B virus (HBV) is a small-enveloped DNA virus causing acute and chronic hepatitis. Despite the existence of an effective prophylactic vaccine and the strong capacity of approved antiviral drugs to suppress viral… read more here.
Keywords: hepatitis; infection; hepatitis virus; chronic hepatitis ... See more keywords
Epigenetic modulation and understanding of HDAC inhibitors in cancer therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119504
Abstract: The role of genetic and epigenetic factors in tumor initiation and progression is well documented. Histone deacetylases (HDACs), histone methyl transferases (HMTs), and DNA methyl transferases. (DNMTs) are the main proteins that are involved in… read more here.
Keywords: understanding hdac; modulation understanding; hdac inhibitors; cancer ... See more keywords
Epigenetic modulation as a therapy in systemic sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology"
DOI: 10.1093/rheumatology/key071
Abstract: SSc is an autoimmune idiopathic disease in which there is an inflammatory component driving fibrosis. The chief cell involved is the myofibroblast, which when activated secretes copious amounts of extracellular matrix that forms deposits, leading… read more here.
Keywords: therapy systemic; fibrosis; systemic sclerosis; rheumatology ... See more keywords
Epigenetic Modulation on Tau Phosphorylation in Alzheimer's Disease
Sign Up to like & getrecommendations! Published in 2019 at "Neural Plasticity"
DOI: 10.1155/2019/6856327
Abstract: Tau hyperphosphorylation is a typical pathological change in Alzheimer's disease (AD) and is involved in the early onset and progression of AD. Epigenetic modification refers to heritable alterations in gene expression that are not caused… read more here.
Keywords: alzheimer disease; tau phosphorylation; phosphorylation; epigenetic modulation ... See more keywords
Abstract P2-04-11: Promotion of immunogenicity using epigenetic modulation and immune checkpoint inhibition in mouse models of breast cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs16-p2-04-11
Abstract: Checkpoint inhibition is a very successful treatment strategy in cancers that are naturally immunogenic by attracting T cells into the tumor microenvironment (TME) and promoting cytotoxic signaling pathways. While this strategy has shown some efficacy… read more here.
Keywords: cancer; epigenetic modulation; checkpoint inhibition; tumor ... See more keywords
Genetic and epigenetic modulation of drug resistance in cancer: Challenges and opportunities.
Sign Up to like & getrecommendations! Published in 2020 at "Current drug metabolism"
DOI: 10.2174/1389200221666200103111539
Abstract: Cancer is a complex disease that has the ability to develop resistance to traditional therapies. The current chemotherapeutic treatment has become increasingly sophisticated, yet it is not 100% effective against disseminated tumours. Anticancer drugs resistance… read more here.
Keywords: drug resistance; drug; resistance; cancer ... See more keywords
Epigenetic modulation and prostate cancer: Paving the way for NK cell anti-tumor immunity
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1152572
Abstract: Immunoepigenetics is a growing field, as there is mounting evidence on the key role played by epigenetic mechanisms in the regulation of tumor immune cell recognition and control of immune cell anti-tumor responses. Moreover, it… read more here.
Keywords: cell; anti tumor; epigenetic modulation; immune ... See more keywords
Minireview: The Epigenetic Modulation of KISS1 in Reproduction and Cancer
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph16142607
Abstract: Epigenetics describes how both lifestyle and environment may affect human health through the modulation of genome functions and without any change to the DNA nucleotide sequence. The discovery of several epigenetic mechanisms and the possibility… read more here.
Keywords: modulation kiss1; modulation; minireview epigenetic; health ... See more keywords
Preliminary Characterization of the Epigenetic Modulation in the Human Mesenchymal Stem Cells during Chondrogenic Process
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179870
Abstract: Regenerative medicine represents a growing hot topic in biomedical sciences, aiming at setting out novel therapeutic strategies to repair or regenerate damaged tissues and organs. For this perspective, human mesenchymal stem cells (hMSCs) play a… read more here.
Keywords: modulation; epigenetic modulation; mesenchymal stem; human mesenchymal ... See more keywords
Epigenetic modulation during hippocampal development.
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical reports"
DOI: 10.3892/br.2018.1160
Abstract: The hippocampus is located in the limbic system and is vital in learning ability, memory formation and emotion regulation, and is associated with depression, epilepsy and mental retardation in an abnormal developmental situation. Several factors… read more here.
Keywords: hippocampal development; development; modulation hippocampal; epigenetic modulation ... See more keywords