Regulatory roles of epigenetic modulators, modifiers and mediators in lung cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2016.11.007
Abstract: Lung cancer as the leading cause of cancer-related deaths can be initiated and progressed by the interaction between dynamically genetic and epigenetic elements, although mechanisms mediating lung cancer development and progression remain unclear. Tumor progenitor… read more here.
Keywords: modifiers mediators; epigenetic modulators; lung cancer; cancer ... See more keywords
Concurrent mutations in other epigenetic modulators portend better prognosis in BCOR-mutated myelodysplastic syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2019-206132
Abstract: Introduction The role of single mutations has been extensively studied myelodysplastic syndromes (MDS), but the impact of genetic aberrations in the context of other mutations is less well understood. BCOR is an epigenetic transcriptional corepressor.… read more here.
Keywords: mutations epigenetic; epigenetic modulators; prognosis; concurrent mutations ... See more keywords
Oncolytic Viruses in Combination Therapeutic Approaches with Epigenetic Modulators: Past, Present, and Future Perspectives
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DOI: 10.3390/cancers13112761
Abstract: Simple Summary Cancer rates have been accelerating significantly in recent years. Despite notable advances having been made in cancer therapy, and numerous studies being currently conducted in clinical trials, research is always looking for new… read more here.
Keywords: combination; epigenetic modulators; combination therapeutic; therapeutic approaches ... See more keywords
Natural Bioactive Products as Epigenetic Modulators for Treating Neurodegenerative Disorders
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DOI: 10.3390/ph16020216
Abstract: Neurodegenerative disorders (NDDs) are major health issues in Western countries. Despite significant efforts, no effective therapeutics for NDDs exist. Several drugs that target epigenetic mechanisms (epidrugs) have been recently developed for the treatment of NDDs,… read more here.
Keywords: epigenetic modulators; modulators treating; bioactive products; natural bioactive ... See more keywords