Garlic‐derived compounds: Epigenetic modulators and their antitumor effects
Sign Up to like & getrecommendations! Published in 2024 at "Phytotherapy Research"
DOI: 10.1002/ptr.8108
Abstract: Cancer is a highly heterogeneous disease that poses a serious threat to human health worldwide. Despite significant advances in the diagnosis and treatment of cancer, the prognosis and survival rate of cancer remain poor due… read more here.
Keywords: garlic derived; cancer; compounds epigenetic; derived compounds ... See more keywords
Regulatory roles of epigenetic modulators, modifiers and mediators in lung cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2016.11.007
Abstract: Lung cancer as the leading cause of cancer-related deaths can be initiated and progressed by the interaction between dynamically genetic and epigenetic elements, although mechanisms mediating lung cancer development and progression remain unclear. Tumor progenitor… read more here.
Keywords: modifiers mediators; epigenetic modulators; lung cancer; cancer ... See more keywords
Concurrent mutations in other epigenetic modulators portend better prognosis in BCOR-mutated myelodysplastic syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2019-206132
Abstract: Introduction The role of single mutations has been extensively studied myelodysplastic syndromes (MDS), but the impact of genetic aberrations in the context of other mutations is less well understood. BCOR is an epigenetic transcriptional corepressor.… read more here.
Keywords: mutations epigenetic; epigenetic modulators; prognosis; concurrent mutations ... See more keywords
Oncolytic Viruses in Combination Therapeutic Approaches with Epigenetic Modulators: Past, Present, and Future Perspectives
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DOI: 10.3390/cancers13112761
Abstract: Simple Summary Cancer rates have been accelerating significantly in recent years. Despite notable advances having been made in cancer therapy, and numerous studies being currently conducted in clinical trials, research is always looking for new… read more here.
Keywords: combination; epigenetic modulators; combination therapeutic; therapeutic approaches ... See more keywords
Nanoplastics as Gene and Epigenetic Modulators of Endocrine Functions: A Perspective
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DOI: 10.3390/ijms26052071
Abstract: Nanoplastics (NPs) represent a major challenge in environmental contamination resulting from the physical, chemical, and biological degradation of plastics. Their characterization requires advanced and expensive methods, which limit routine analyses. The biological effects of NPs… read more here.
Keywords: gene epigenetic; endocrine functions; modulators endocrine; functions perspective ... See more keywords
Reversing Epigenetic Dysregulation in Neurodegenerative Diseases: Mechanistic and Therapeutic Considerations
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DOI: 10.3390/ijms26104929
Abstract: Epigenetic dysregulation has emerged as an important player in the pathobiology of neurodegenerative diseases (NDDs), such as Alzheimer’s, Parkinson’s, and Huntington’s diseases. Aberrant DNA methylation, histone modifications, and dysregulated non-coding RNAs have been shown to… read more here.
Keywords: epigenetic dysregulation; reversing epigenetic; dysregulation neurodegenerative; epigenetic modulators ... See more keywords
Natural Bioactive Products as Epigenetic Modulators for Treating Neurodegenerative Disorders
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16020216
Abstract: Neurodegenerative disorders (NDDs) are major health issues in Western countries. Despite significant efforts, no effective therapeutics for NDDs exist. Several drugs that target epigenetic mechanisms (epidrugs) have been recently developed for the treatment of NDDs,… read more here.
Keywords: epigenetic modulators; modulators treating; bioactive products; natural bioactive ... See more keywords