Insights into epigenetic patterns in mammalian early embryos
Sign Up to like & getrecommendations! Published in 2020 at "Protein & Cell"
DOI: 10.1007/s13238-020-00757-z
Abstract: Mammalian fertilization begins with the fusion of two specialized gametes, followed by major epigenetic remodeling leading to the formation of a totipotent embryo. During the development of the pre-implantation embryo, precise reprogramming progress is a… read more here.
Keywords: epigenetic patterns; embryo; insights epigenetic; mammalian early ... See more keywords
Epigenetic signatures in cancer: proper controls, current challenges and the potential for clinical translation
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DOI: 10.1186/s13073-021-00837-7
Abstract: Epigenetic alterations are associated with normal biological processes such as aging or differentiation. Changes in global epigenetic signatures, together with genetic alterations, are driving events in several diseases including cancer. Comparative studies of cancer and… read more here.
Keywords: epigenetic patterns; cancer epigenomes; epigenetic signatures; signatures cancer ... See more keywords
Novel Subgroups of Type 2 Diabetes Display Different Epigenetic Patterns That Associate With Future Diabetic Complications
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DOI: 10.2337/dc21-2489
Abstract: OBJECTIVE Type 2 diabetes (T2D) was recently reclassified into severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), mild obesity-related diabetes (MOD), and mild age-related diabetes (MARD), which have different risk of complications. We explored whether… read more here.
Keywords: subgroup unique; methylation; diabetic complications; epigenetic patterns ... See more keywords