Identification of a unique epigenetic profile in women with diminished ovarian reserve.
Sign Up to like & getrecommendations! Published in 2020 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2020.09.009
Abstract: OBJECTIVE To investigate whether epigenetic profiles of mural granulosa cells (MGC) and leukocytes from women with diminished ovarian reserve (DOR) differ from those of women with normal or high ovarian reserve. DESIGN Prospectively collected material… read more here.
Keywords: reserve; diminished ovarian; women diminished; ovarian reserve ... See more keywords
Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype
Sign Up to like & getrecommendations! Published in 2018 at "OncoImmunology"
DOI: 10.1080/2162402x.2017.1393596
Abstract: ABSTRACT Pancreatic Ductal Adenocarcinoma (PDA) is characterized by a complex tumor microenvironment that supports its progression, aggressiveness and resistance to therapies. The delicate interplay between cancer and immune cells creates the conditions for PDA development,… read more here.
Keywords: phenotype; tumor associated; anti tumor; infiltrating cells ... See more keywords
Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression
Sign Up to like & getrecommendations! Published in 2017 at "BMC Psychiatry"
DOI: 10.1186/s12888-017-1515-8
Abstract: BackgroundIt is well established that there is a link between inflammation and depression, with several studies reporting increased circulating levels of the pro-inflammatory cytokine, interleukin-6 (IL6), in depressed individuals. Peripheral epigenetic marks, including DNA methylation,… read more here.
Keywords: investigating epigenetic; depression; methylation; gene ... See more keywords