YEATS Domains as Novel Epigenetic Readers: Structures, Functions, and Inhibitor Development.
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DOI: 10.1021/acschembio.1c00945
Abstract: Interpretation of the histone posttranslational modifications (PTMs) by effector proteins, or readers, is an important epigenetic mechanism to regulate gene function. YEATS domains have been recently identified as novel readers of histone lysine acetylation and… read more here.
Keywords: development yeats; yeats domains; development; epigenetic readers ... See more keywords
Expansion microscopy allows high resolution single cell analysis of epigenetic readers
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac521
Abstract: Abstract Interactions between epigenetic readers and histone modifications play a pivotal role in gene expression regulation and aberrations can enact etiopathogenic roles in both developmental and acquired disorders like cancer. Typically, epigenetic interactions are studied… read more here.
Keywords: expansion microscopy; localization; epigenetic readers; microscopy ... See more keywords