Epigenetic regulation of cancer stem cell formation and maintenance
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33398
Abstract: Cancerous tumours contain a rare subset of cells with stem‐like properties that are termed cancer stem cells (CSCs). CSCs are defined by their ability to divide both symmetrically and asymmetrically, to initiate new tumour growth… read more here.
Keywords: cancer; epigenetic regulation; cancer stem; cscs ... See more keywords
Mechanisms of epigenetic regulation of transcription by lncRNAs in plants
Sign Up to like & getrecommendations! Published in 2022 at "IUBMB Life"
DOI: 10.1002/iub.2681
Abstract: Long noncoding RNAs (lncRNAs) are an ubiquitous feature of eukaryotic genomes and in recent decades have been shown to be highly abundant and varied. Many prominent examples have been described as having essential roles in… read more here.
Keywords: transcription; mechanisms epigenetic; lncrnas plants; epigenetic regulation ... See more keywords
Curcumin suppressed the prostate cancer by inhibiting JNK pathways via epigenetic regulation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22049
Abstract: Curcumin is a component of turmeric and is isolated from the rhizomes of the plant Curcuma longa. Curcumin was reported to have therapeutic effects on prostate cancer. Yet the molecular mechanism of curcumin remains unclear.… read more here.
Keywords: epigenetic regulation; prostate cancer; curcumin;
Epigenetic regulation - contribution to herbicide resistance in weeds?
Sign Up to like & getrecommendations! Published in 2018 at "Pest management science"
DOI: 10.1002/ps.4727
Abstract: Continuous use of herbicides has resulted in the evolution of resistance to all major herbicide modes of action worldwide. Besides the well-documented cases of newly acquired resistance through genetic changes, epigenetic regulation may also contribute… read more here.
Keywords: herbicide resistance; epigenetic regulation; resistance; resistance weeds ... See more keywords
Genetic and Epigenetic Regulation of Organic Cation Transporters.
Sign Up to like & getrecommendations! Published in 2021 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2021_450
Abstract: Organic cation transporters (OCTs) of the solute carrier family (SLC) 22 are the subject of intensive research because they mediate the transport of many clinically-relevant drugs such as the antidiabetic agent metformin, the opioid tramadol,… read more here.
Keywords: epigenetic regulation; organic cation; oct2 oct3; cation transporters ... See more keywords
Epigenetic Regulation of Chromatin in Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-32656-2_17
Abstract: Epigenetics refers to mitotically/meiotically heritable mechanisms that regulate gene transcription without a need for changes in the DNA code. Covalent modifications of DNA, in the form of methylation, and histone post-translational modifications, in the form… read more here.
Keywords: cancer; epigenetic regulation; regulation chromatin; prostate cancer ... See more keywords
Epigenetic Regulation of Human Neural Stem Cell Differentiation.
Sign Up to like & getrecommendations! Published in 2018 at "Results and problems in cell differentiation"
DOI: 10.1007/978-3-319-93485-3_5
Abstract: Emerging evidence has demonstrated that epigenetic programs influence many aspects of neural stem cell (NSC) behavior, including proliferation and differentiation. It is becoming apparent that epigenetic mechanisms, such as DNA methylation, histone modifications, and noncoding… read more here.
Keywords: regulation human; stem cell; differentiation; stem ... See more keywords
Epigenetic Regulation of Vascular Aging and Age-Related Vascular Diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-1117-8_4
Abstract: Vascular aging refers to the structural and functional defects that occur in the aorta during the aging process and is characterized by increased vascular cell senescence, vascular dyshomeostasis, and vascular remodeling. Vascular aging is a… read more here.
Keywords: age related; epigenetic regulation; vascular aging; regulation ... See more keywords
Treg Cells and Epigenetic Regulation.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-6407-9_6
Abstract: The discovery of the epigenetic regulation of Treg cells, a cell population with fundamental immunoregulatory properties, has shed considerable insights into an understanding of the role of these cells in health and disease. Research over… read more here.
Keywords: cells epigenetic; treg cells; regulation treg; epigenetic regulation ... See more keywords
Transcriptional and Epigenetic Regulation of Cardiac Electrophysiology
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Cardiology"
DOI: 10.1007/s00246-019-02160-w
Abstract: Spatiotemporal gene expression during cardiac development is a highly regulated process. Activation of key signaling pathways involved in electrophysiological programming, such as Notch and Wnt signaling, occurs in early cardiovascular development and these pathways are… read more here.
Keywords: cardiac electrophysiology; transcriptional epigenetic; regulation cardiac; epigenetic regulation ... See more keywords
Epigenetic regulation of muscle development
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Muscle Research and Cell Motility"
DOI: 10.1007/s10974-017-9469-5
Abstract: In eukaryote cells, chromatin appears in several forms and is composed of genomic DNA, protein and RNA. The protein content of chromatin is composed primarily of core histones that are packaged into nucleosomes resulting in… read more here.
Keywords: dna; muscle; muscle development; epigenetic regulation ... See more keywords