Epigenetic signatures of methylated DNA cytosine in Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aaw2880
Abstract: The discovery of AD epigenetic signatures lays a molecular basis for new methods to detect early AD using patient blood cells. Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is the most common untreatable form of… read more here.
Keywords: epigenetic signatures; alzheimer disease; signatures methylated; cytosine ... See more keywords
Abstract 3021: Epigenetic signatures of virus-associated cervical cancer in women living with HIV
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3021
Abstract: Background: Low- and middle-income countries are facing a high health burden of cervical cancer (CC). The situation is worsened by a high prevalence of human immunodeficiency virus (HIV). We aim to identify epigenetic signatures to… read more here.
Keywords: cervical cancer; hiv; epigenetic signatures; living hiv ... See more keywords
Epigenetic signatures in cancer: proper controls, current challenges and the potential for clinical translation
Sign Up to like & getrecommendations! Published in 2021 at "Genome Medicine"
DOI: 10.1186/s13073-021-00837-7
Abstract: Epigenetic alterations are associated with normal biological processes such as aging or differentiation. Changes in global epigenetic signatures, together with genetic alterations, are driving events in several diseases including cancer. Comparative studies of cancer and… read more here.
Keywords: epigenetic patterns; cancer epigenomes; epigenetic signatures; signatures cancer ... See more keywords
Epigenetic signatures of gestational diabetes mellitus on cord blood methylation
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Epigenetics"
DOI: 10.1186/s13148-017-0329-3
Abstract: BackgroundIntrauterine exposure to gestational diabetes mellitus (GDM) confers a lifelong increased risk for metabolic and other complex disorders to the offspring. GDM-induced epigenetic modifications modulating gene regulation and persisting into later life are generally assumed… read more here.
Keywords: gestational diabetes; methylation; epigenetic signatures; cord ... See more keywords
Circular RNAs: New Epigenetic Signatures in Viral Infections
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.01853
Abstract: Covalent closed circular RNAs (circRNAs) can act as a bridge between non-coding RNAs and coding messenger RNAs. CircRNAs are generated by a back-splicing mechanism during post-transcriptional processing and are abundantly expressed in eukaryotic cells. CircRNAs… read more here.
Keywords: new epigenetic; signatures viral; circular rnas; epigenetic signatures ... See more keywords
Epigenetic Signatures in Arterial Hypertension: Focus on the Microvasculature
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054854
Abstract: Systemic arterial hypertension (AH) is a multifaceted disease characterized by accelerated vascular aging and high cardiometabolic morbidity and mortality. Despite extensive work in the field, the pathogenesis of AH is still incompletely understood, and its… read more here.
Keywords: signatures arterial; hypertension focus; arterial hypertension; epigenetic signatures ... See more keywords
Epigenetic Signatures of Smoking in Five Brain Regions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12040566
Abstract: (1) Background: Epigenome-wide association studies (EWAS) in peripheral blood have repeatedly found associations between tobacco smoking and aberrant DNA methylation (DNAm), but little is known about DNAm signatures of smoking in the human brain, which… read more here.
Keywords: smoking five; brain regions; epigenetic signatures; signatures smoking ... See more keywords