Articles with "epigenetic target" as a keyword



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An epigenetic target for autism

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Published in 2018 at "Science Translational Medicine"

DOI: 10.1126/scitranslmed.aat4476

Abstract: A transient 3-day course of treatment with a histone deacetylase inhibitor persistently rescues atypical social behavior in a Shank3-deficiency mouse model of autism. A transient 3-day course of treatment with a histone deacetylase inhibitor persistently… read more here.

Keywords: target autism; autism; epigenetic target; medicine ... See more keywords

Mesothelin as a Signal Pathways and Epigenetic Target in Cancer Therapy

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Published in 2025 at "Cancers"

DOI: 10.3390/cancers17071118

Abstract: Simple Summary Mesothelin, a glycoprotein-based tumor antigen is elevated in several malignancies. It contributes to tumor aggression, metastasis, chemotherapy resistance and is linked with poor prognosis. MSLN expression is regulated by epigenetic changes, which control… read more here.

Keywords: epigenetic target; therapy; target cancer; signal pathways ... See more keywords