Epigenetic and Transcriptional Variability Shape Phenotypic Plasticity
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DOI: 10.1002/bies.201700148
Abstract: Epigenetic and transcriptional variability contribute to the vast diversity of cellular and organismal phenotypes and are key in human health and disease. In this review, we describe different types, sources, and determinants of epigenetic and… read more here.
Keywords: epigenetic transcriptional; phenotypic plasticity; variability; transcriptional variability ... See more keywords
Epigenetic and transcriptional regulation of osteoclast differentiation.
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DOI: 10.1016/j.bone.2020.115471
Abstract: Osteoclasts are derived from mononuclear phagocyte lineage cells and are indispensable for bone resorption. Recent findings suggest that fetal yolk sac macrophage progenitors give rise to neonatal osteoclasts, while hematopoietic stem cell-derived cells, such as… read more here.
Keywords: epigenetic transcriptional; osteoclast differentiation; regulation osteoclast; factor ... See more keywords
Establishment and inheritance of epigenetic transcriptional memory
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DOI: 10.3389/fmolb.2022.977653
Abstract: For certain inducible genes, the rate and molecular mechanism of transcriptional activation depends on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation and requires both changes in chromatin structure… read more here.
Keywords: transcriptional memory; epigenetic transcriptional; rnapii; establishment inheritance ... See more keywords