The epigenetic treatment remodel genome-wide histone H4 hyper-acetylation patterns and affect signaling pathways in acute promyelocytic leukemia cells.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173641
Abstract: Although majority of acute promyelocytic leukemia (APL) patients achieve complete remission after the standard treatment, 5-10% of patients are shown to relapse or develop resistance to treatment. In such cases, medications that target epigenetic processes… read more here.
Keywords: signaling pathways; promyelocytic leukemia; treatment; epigenetic treatment ... See more keywords
Epigenetic Treatment of Neurodegenerative Ophthalmic Disorders: An Eye Toward the Future
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DOI: 10.1089/biores.2017.0036
Abstract: Abstract Eye disease is one of the primary medical conditions that requires attention and therapeutic intervention in ageing populations worldwide. Further, the global burden of diabetes and obesity, along with heart disease, all lead to… read more here.
Keywords: ophthalmic disorders; epigenetic treatment; disorders eye; treatment neurodegenerative ... See more keywords