Targeting epigenetics using synthetic lethality in precision medicine
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-018-2866-0
Abstract: Technological breakthroughs in genomics have had a significant impact on clinical therapy for human diseases, allowing us to use patient genetic differences to guide medical care. The “synthetic lethal approach” leverages on cancer-specific genetic rewiring… read more here.
Keywords: medicine; targeting epigenetics; epigenetics using; lethality precision ... See more keywords