Epigenomic Changes Prime PDAC Metastasis.
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DOI: 10.1158/2159-8290.cd-nb2017-025
Abstract: Widespread chromatin modifications and DNA methylation could be responsible for inducing the spread of pancreatic ductal adenocarcinoma cells to distant sites, according to recent research. The findings also implicate glucose metabolism as a driver of… read more here.
Keywords: epigenomic changes; changes prime; metastasis; prime pdac ... See more keywords
Single-housing–induced islet epigenomic changes are related to polymorphisms in diabetic KK mice
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DOI: 10.26508/lsa.202302099
Abstract: This study demonstrates that non-coding variants in KK mice, a polygenic model of type 2 diabetes, may be involved in the development of diabetes via epigenetic mechanisms during social isolation. A lack of social relationships… read more here.
Keywords: mice; housing induced; epigenomic changes; diabetic mice ... See more keywords