Explaining cancer type specific mutations with transcriptomic and epigenomic features in normal tissues
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29861-1
Abstract: Most cancer driver genes are involved in generic cellular processes such as DNA repair, cell proliferation and cell adhesion, yet their mutations are often confined to specific cancer types. To resolve this paradox, we explained… read more here.
Keywords: normal tissues; epigenomic features; cancer; gene ... See more keywords
Genomic and Epigenomic Features of Glioblastoma Multiforme and its Biomarkers
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/4022960
Abstract: Glioblastoma multiforme is a serious and life-threatening tumor of central nervous system, characterized by aggressive behavior, poor prognosis, and low survival rate. Despite of the availability of aggressive antitumor therapeutic regimen for glioblastoma (radiotherapy followed… read more here.
Keywords: multiforme biomarkers; prognosis; genomic epigenomic; features glioblastoma ... See more keywords
Epigenomic Features and Potential Functions of K+ and Na+ Favorable DNA G-Quadruplexes in Rice
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DOI: 10.3390/ijms23158404
Abstract: DNA G-quadruplexes (G4s) are non-canonical four-stranded DNA structures involved in various biological processes in eukaryotes. Molecularly crowded solutions and monovalent cations have been reported to stabilize in vitro and in vivo G4 formation. However, how… read more here.
Keywords: dna; dna quadruplexes; specific g4s; features potential ... See more keywords