Articles with "epigenomic integration" as a keyword



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Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-39395-9

Abstract: Glucocorticoid receptor is a transcription factor that is ubiquitously expressed. Glucocorticoids are circadian steroids that regulate a wide range of bodily functions, including immunity. Here we report that synthetic glucocorticoids affect 1035 mRNAs in isolated… read more here.

Keywords: epigenomic integration; glucocorticoid response; response; extensive epigenomic ... See more keywords