Interferon target-gene expression and epigenomic signatures in health and disease
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DOI: 10.1038/s41590-019-0466-2
Abstract: Multiple type I interferons and interferon-γ (IFN-γ) are expressed under physiological conditions and are increased by stress and infections, and in autoinflammatory and autoimmune diseases. Interferons activate the Jak–STAT signaling pathway and induce overlapping patterns… read more here.
Keywords: autoimmune diseases; interferon; interferon epigenomic; expression ... See more keywords
Epigenomic Signatures in Myelodysplastic Syndrome Patients As Predictors of Donor Compatibility and Transplant Outcome
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-127124
Abstract: Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic stem cell disorders for which allogeneic hematopoietic stem cell transplantation (HCT) is currently the only curative treatment. Epigenetic lesions are considered a major pathogenetic determinant in… read more here.
Keywords: methylation; relapsed patients; dmrs; transplant ... See more keywords