Cannabinoids in epilepsy: Clinical efficacy and pharmacological considerations.
Sign Up to like & getrecommendations! Published in 2020 at "Neurologia"
DOI: 10.1016/j.nrl.2020.02.005
Abstract: INTRODUCTION Advances in the development of drugs with novel mechanisms of action have not been sufficient to significantly reduce the percentage of patients presenting drug-resistant epilepsy. This lack of satisfactory clinical results has led to… read more here.
Keywords: clinical efficacy; mechanisms action; efficacy; cannabinoids epilepsy ... See more keywords
Clinical Course May Be Independent from Neuroimaging in DEPDC-5-Related Epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Neuropediatrics"
DOI: 10.1055/a-2067-5096
Abstract: Abstract DEPDC5 is an upstream repressor of the mechanistic target of rapamycin pathway via the GATOR-1 complex. Pathogenic variants causing loss of function typically result in familial focal epilepsy with variable foci. Neuroimaging may either… read more here.
Keywords: epilepsy clinical; clinical course; may independent; course may ... See more keywords
Cognitive deterioration in adult epilepsy: clinical characteristics of “Accelerated Cognitive Ageing”
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurologica Scandinavica"
DOI: 10.1111/ane.12700
Abstract: “Epileptic dementia” is reported in adults with childhood‐onset refractory epilepsy. Cognitive deterioration can also occur in a “second‐hit model”. read more here.
Keywords: deterioration; deterioration adult; adult epilepsy; epilepsy clinical ... See more keywords