EEG synchronization measures predict epilepsy-related BOLD-fMRI fluctuations better than commonly used univariate metrics
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2017.12.038
Abstract: OBJECTIVE We hypothesize that the hypersynchronization associated with epileptic activity is best described by EEG synchronization measures, and propose to use these as predictors of epilepsy-related BOLD fluctuations. METHODS We computed the phase synchronization index… read more here.
Keywords: eeg synchronization; better commonly; related bold; epilepsy related ... See more keywords
Structural basis of epilepsy-related ligand–receptor complex LGI1–ADAM22
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03947-w
Abstract: Epilepsy is a common brain disorder throughout history. Epilepsy-related ligand–receptor complex, LGI1–ADAM22, regulates synaptic transmission and has emerged as a determinant of brain excitability, as their mutations and acquired LGI1 autoantibodies cause epileptic disorders in… read more here.
Keywords: receptor; lgi1; epilepsy related; lgi1 adam22 ... See more keywords
Case-control study developing Scottish Epilepsy Deaths Study Score to predict epilepsy-related death
Sign Up to like & getrecommendations! Published in 2022 at "Brain"
DOI: 10.1093/brain/awac463
Abstract: Abstract This study aimed to develop a risk prediction model for epilepsy-related death in adults. In this age- and sex-matched case-control study, we compared adults (aged ≥16 years) who had epilepsy-related death between 2009 and… read more here.
Keywords: deaths study; epilepsy deaths; study score; epilepsy ... See more keywords
Clinical and molecular analysis of epilepsy-related genes in patients with Dravet syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000013565
Abstract: Abstract Dravet syndrome is considered to be one of the most severe types of genetic epilepsy. Mutations in SCN1A gene have been found to be responsible for at least 80% of patients with Dravet syndrome,… read more here.
Keywords: related genes; patients dravet; epilepsy related; dravet syndrome ... See more keywords
Epilepsy‐related stigma and attitudes: Systematic review of screening instruments and interventions ‐ Report by the International League Against Epilepsy Task Force on Stigma in Epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17133
Abstract: This is a systematic review aimed at summarizing the evidence related to instruments that have been developed to measure stigma or attitudes toward epilepsy and on stigma‐reducing interventions. read more here.
Keywords: stigma; stigma attitudes; systematic review; epilepsy ... See more keywords
Review: The past, present and future challenges in epilepsy‐related and sudden deaths and biobanking
Sign Up to like & getrecommendations! Published in 2018 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12453
Abstract: Awareness and research on epilepsy‐related deaths (ERD), in particular Sudden Unexpected Death in Epilepsy (SUDEP), have exponentially increased over the last two decades. Most publications have focused on guidelines that inform clinicians dealing with these… read more here.
Keywords: challenges epilepsy; review past; epilepsy related; present future ... See more keywords
No Time to Die – Avoidable Death in Epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsy Currents"
DOI: 10.1177/15357597221086390
Abstract: Objective: This study was undertaken to investigate the trends and mechanisms of epilepsy-related deaths in Scotland, highlighting the proportion that were potentially avoidable. Methods: This was a retrospective observational data-linkage study of administrative data from… read more here.
Keywords: potentially avoidable; related deaths; death; mortality ... See more keywords
Early MRI in Epilepsy: A Picture Is Worth a Thousand Preventable Seizures
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DOI: 10.1177/15357597221138509
Abstract: Structural Neuroimaging in Adults and Adolescents With Newly Diagnosed Focal Epilepsy: The Human Epilepsy Project Bank AM, Kuzniecky R, Knowlton RC, Cascino GD, Jackson G, Pardoe HR; for the Human Epilepsy Project Investigators. Neurology. 2022.… read more here.
Keywords: newly diagnosed; mri; focal epilepsy; epilepsy ... See more keywords
Structural Neuroimaging in Adults and Adolescents With Newly Diagnosed Focal Epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000201125
Abstract: Background and Objectives Identification of an epileptogenic lesion on structural neuroimaging in individuals with focal epilepsy is important for management and treatment planning. The objective of this study was to determine the frequency of MRI-identified… read more here.
Keywords: structural neuroimaging; newly diagnosed; focal epilepsy; epilepsy ... See more keywords
Cost of epilepsy-related health care encounters in the United States.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of managed care & specialty pharmacy"
DOI: 10.18553/jmcp.2020.20111
Abstract: BACKGROUND: The cost of epilepsy is usually reported as total expenditure over a certain period. However, with the increased availability of acute treatments for use in the community setting, intermittent, single-seizure treatment is now possible… read more here.
Keywords: health care; health; epilepsy related; care encounters ... See more keywords
Perceived epilepsy-related stigma is linked to the socioeconomic status of the residence
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.952585
Abstract: Purpose Epilepsy is one of the most common neurological disorders with high costs for the healthcare systems and great suffering for patients. Beyond seizures, psychosocial comorbidities can have detrimental effects on the well-being of people… read more here.
Keywords: stigma; structural ses; socioeconomic status; related stigma ... See more keywords