Mini Review on Forced Degradation Studies on Anti-Epileptic Drugs and Beyond.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmac070
Abstract: In this review on the forced degradation studies on anti-epileptic drugs and the development of validated stability-indicating assay methods for drug substances and products at a condition more severe than accelerated condition (i.e. 40 ± 2°C, 75 ± 5%… read more here.
Keywords: epileptic drugs; studies anti; forced degradation; degradation ... See more keywords
Anti‐epileptic drugs induce cutaneous lymphocyte‐associated antigen downregulation leading to potential human herpes virus‐7 reactivation in clinically asymptomatic patients
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.14493
Abstract: Editor Anti-epileptic drugs (AEDs) are known to cause cutaneous adverse drug-induced reactions. The pathogenesis of these drug-induced reactions remains poorly understood. In our previous multicenter prospective study, we evidenced reactivation of Epstein–Barr virus (EBV), human… read more here.
Keywords: anti epileptic; epileptic drugs; herpes virus; reactivation ... See more keywords
G302 Comparison of 4-weeks versus 12-weeks anti-convulsant therapy for acute symptomatic seizures in children with acute encephalitis syndrome- an open-label, randomised controlled trial
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2018-rcpch.294
Abstract: Background There exists poor evidence-base and conflicting literature regarding optimum duration of anti-epileptic drugs for acute symptomatic seizures in central nervous system infections. A duration of one to three-months of anti-epileptic drugs has been suggested… read more here.
Keywords: encephalitis syndrome; anti epileptic; epileptic drugs; acute encephalitis ... See more keywords
Protocol for a prospective observational study of adverse drug reactions of anti-epileptic drugs in children in the UK
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Paediatrics Open"
DOI: 10.1136/bmjpo-2017-000116
Abstract: Background Epilepsy is a common chronic disease of children that can be treated with anti-epileptic drugs (AEDs). AEDs, however, have significant side effects. Newer AEDs are thought to have fewer side effects. There have, however,… read more here.
Keywords: anti epileptic; epileptic drugs; drug reactions; study ... See more keywords
Phenotypic screening using waveform analysis of synchronized calcium oscillations in primary cortical cultures
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DOI: 10.1371/journal.pone.0271782
Abstract: At present, in vitro phenotypic screening methods are widely used for drug discovery. In the field of epilepsy research, measurements of neuronal activities have been utilized for predicting efficacy of anti-epileptic drugs. Fluorescence measurements of… read more here.
Keywords: analysis; phenotypic screening; calcium oscillations; epileptic drugs ... See more keywords
Interactome overlap between risk genes of epilepsy and targets of anti-epileptic drugs
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0272428
Abstract: Aanti-epileptic drugs have been used for treating epilepsy for decades, meanwhile, more than one hundred genes have been identified to be associated with risk of epilepsy; however, the interaction mechanism between anti-epileptic drugs and risk… read more here.
Keywords: network; risk genes; risk; genes epilepsy ... See more keywords
Effects of anti-epileptic drugs on the oral health of paediatric patients.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of paediatric dentistry"
DOI: 10.23804/ejpd.2023.24.01.08
Abstract: AIM To evaluate the effects of epilepsy therapy on the oral health in paediatrics patients. MATERIALS The test has involved 57 patients. The patients were stratified in three groups: monotherapy group, politherapy group and control… read more here.
Keywords: health; oral health; group; effects anti ... See more keywords
Common variants of APOE are associated with anti-epileptic drugs resistance in Han Chinese patients
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Neuroscience"
DOI: 10.3109/00207454.2015.1137295
Abstract: Purpose/aim of the study: Apolipoprotein E (APOE) has been implicated as one of the susceptibility genes for some subtypes of epilepsy and may be related to anti-epileptic drugs resistance. The purpose of this study was… read more here.
Keywords: anti epileptic; epileptic drugs; drugs resistance; drug ... See more keywords
Efficacy and Utilization Patterns of Anti-Epileptic Drugs in the Management of Neonatal Seizures: A Comparative Exploration
Sign Up to like & getrecommendations! Published in 2022 at "Neurology India"
DOI: 10.4103/0028-3886.344647
Abstract: Background: Management of neonatal seizures with available limited guidelines across different gestation can cause long-term neurological and cognitive impairment. Objectives: To compare utilization and observe the efficacy of anti-epileptic drugs in the treatment of neonatal… read more here.
Keywords: line agent; neonatal seizures; epileptic drugs; anti epileptic ... See more keywords