Inhibition of microRNA-34a Suppresses Epileptiform Discharges Through Regulating Notch Signaling and Apoptosis in Cultured Hippocampal Neurons
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02772-x
Abstract: Epilepsy is characterized by recurrent unprovoked seizures and some seizures can cause neuronal apoptosis, which is possible to make contributions to the epilepsy phenotype, impairments in cognitive function or even epileptogenesis. Moreover, many studies have… read more here.
Keywords: apoptosis; notch signaling; epileptiform discharges; regulating notch ... See more keywords
The influence of the abundance and morphology of epileptiform discharges on diagnostic accuracy: How many spikes you need to spot in an EEG
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2021.03.045
Abstract: OBJECTIVE The operational definition of interictal epileptiform discharges (IEDs) of the International Federation of Clinical Neurophysiology (IFCN) described six morphological criteria. Our objective was to assess the impact of pattern-repetition in the EEG-recording, on the… read more here.
Keywords: accuracy; diagnostic accuracy; morphology; epileptiform discharges ... See more keywords
Effect of priming low-frequency magnetic fields on zero-Mg2+ -induced epileptiform discharges in rat hippocampal slices
Sign Up to like & getrecommendations! Published in 2020 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2020.106464
Abstract: During the process of seizures, the addition of low-frequency magnetic fields has been proved to be an effective method to suppress epileptic discharges. However, whether adding magnetic fields before the appearance of epileptic discharges can… read more here.
Keywords: magnetic fields; frequency magnetic; frequency; hippocampal slices ... See more keywords
Artificial neural network trained on smartphone behavior can trace epileptiform activity in epilepsy
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102538
Abstract: Summary A range of abnormal electrical activity patterns termed epileptiform discharges can occur in the brains of persons with epilepsy. These epileptiform discharges can be monitored and recorded with implanted devices that deliver therapeutic neurostimulation.… read more here.
Keywords: neural network; smartphone; epileptiform activity; artificial neural ... See more keywords
Camphor elicits epileptiform discharges in snail neurons: The role of ion channels modulation
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2015.12.012
Abstract: HIGHLIGHTSThe effects of camphor on the activity of snail neurons were studied.CAM (0.25 mM) reduced afterhyperpolarization duration and disrupted firing precision.CAM (0.5 mM) suppressed falling phase and AHP and increased the firing rate.CAM (1.5 mM)… read more here.
Keywords: camphor; ion channels; ion; epileptiform discharges ... See more keywords
The relationship between epileptiform discharges and background activity in the visual analysis of electroencephalographic examinations in dogs with seizures of different etiologies.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary journal"
DOI: 10.1016/j.tvjl.2017.03.003
Abstract: Electroencephalographic (EEG) recordings in 125 outpatient dogs with various epileptiform encephalopathies were acquired under medetomidine sedation using subdermal wire electrodes. The features of canine EEG (background activity [BGA] and epileptiform discharges [EDs]) were assessed, described… read more here.
Keywords: analysis; background activity; group; epileptiform discharges ... See more keywords
Transplanting GABAergic Neurons Differentiated from Neural Stem Cells into Hippocampus Inhibits Seizures and Epileptiform Discharges in Pilocarpine-Induced Temporal Lobe Epilepsy Model.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.01.245
Abstract: OBJECTIVE This study aimed to explore whether intrahippocampal transplantation of GABAergic neurons generated in vitro ameliorated seizures and epileptiform discharges via increasing γ-aminobutyric acid (GABA)-associated inhibition mediated by the addition of new GABAergic neurons. METHODS Neural… read more here.
Keywords: group; gaba group; epileptiform discharges; seizures epileptiform ... See more keywords
Low-intensity ultrasound suppresses low-Mg2+-induced epileptiform discharges in juvenile mouse hippocampal slices.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neural engineering"
DOI: 10.1088/1741-2552/ab0b9a
Abstract: OBJECTIVE It has been shown that low-intensity ultrasound (LIUS) can suppress seizures in some laboratory studies. However, the mechanism of the suppression effect of LIUS remains unclear. The goal of this study is to investigate… read more here.
Keywords: hippocampal slices; intensity ultrasound; epileptiform discharges; mouse hippocampal ... See more keywords
Sensor selection and miniaturization limits for detection of interictal epileptiform discharges with wearable EEG
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Neural Engineering"
DOI: 10.1088/1741-2552/acb231
Abstract: Objective. The goal of this paper is to investigate the limits of electroencephalography (EEG) sensor miniaturization in a set-up consisting of multiple galvanically isolated EEG units to record interictal epileptiform discharges (IEDs), referred to as… read more here.
Keywords: epileptiform discharges; eeg sensor; detection; eeg ... See more keywords
0897 Sleep Architecture and Epileptiform Discharges in Rett Syndrome
Sign Up to like & getrecommendations! Published in 2023 at "SLEEP"
DOI: 10.1093/sleep/zsad077.0897
Abstract: Rett syndrome (RTT) is an X-linked dominant neurodevelopmental disorder affecting females and is linked to mutations in the methyl-CpG-binding protein 2 (MeCP2) gene. Sleep issues and frequent epileptiform discharges are common in RTT. Typical comorbidities… read more here.
Keywords: epileptiform discharges; 0897 sleep; rett syndrome; rtt patients ... See more keywords
Distributed source localization of epileptiform discharges in juvenile myoclonic epilepsy: Standardized low-resolution brain electromagnetic tomography (sLORETA) Study
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029625
Abstract: Juvenile myoclonic epilepsy (JME) is a common generalized epilepsy syndrome considered the prototype of idiopathic generalized epilepsy. To date, generalized and focal seizures have been the fundamental concepts for classifying seizure types. In several studies,… read more here.
Keywords: epileptiform discharges; standardized low; source localization; source ... See more keywords