KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity
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DOI: 10.3390/biomedicines10020212
Abstract: Kasugamycin (KSM), an aminoglycoside antibiotic, is composed of three chemical moieties: D-chiro-inositol, kasugamine and glycine imine. Despite being discovered more than 50 years ago, the biosynthetic pathway of KSM remains an unresolved puzzle. Here we… read more here.
Keywords: epimerase primes; kasq epimerase; kasugamycin; aminoglycoside antibiotic ... See more keywords