Molecular properties of epimutation hotspots.
Sign Up to like & getrecommendations! Published in 2022 at "Nature plants"
DOI: 10.1038/s41477-021-01086-7
Abstract: Mistakes in the maintenance of CG methylation are a source of heritable epimutations in plants. Multigenerational surveys indicate that the rate of these stochastic events varies substantially across the genome, with some regions harbouring localized… read more here.
Keywords: molecular properties; properties epimutation; methylation; epimutation hotspots ... See more keywords
DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Epigenetics"
DOI: 10.1186/s13148-021-01127-0
Abstract: Background Mutations in LMNA , encoding lamin A/C, lead to a variety of diseases known as laminopathies including dilated cardiomyopathy (DCM) and skeletal abnormalities. Though previous studies have investigated the dysregulation of gene expression in… read more here.
Keywords: analysis reveals; methylation; epimutation hotspots; dilated cardiomyopathy ... See more keywords